FACULTY RESEARCH

Faculty List

Michael E Phelps, Ph.D.

Work Email Address: mphelps@mednet.ucla.edu

Office Phone Number: 310-825-6539

Mailing Address:
Mail Code: 173517
Los Angeles, CA 90095

Work Address:
23-138 CHS, 10833 Le Conte Ave.
Los Angeles, CA 90095

Department / Division Affiliations
Norton Simon Professor, Molecular & Medical Pharmacology
Chair, Molecular & Medical Pharmacology
Director, Crump Institute for Molecular Imaging
Professor, Biomathematics, Pathology and Laboratory Medicine


Publications
Keng Pei Yuin, Chen Supin, Ding Huijiang, Sadeghi Saman, Shah Gaurav J, Dooraghi Alex, Phelps Michael E, Satyamurthy Nagichettiar, Chatziioannou Arion F, Kim Chang-Jin Cj, van Dam R Michael Micro-chemical synthesis of molecular probes on an electronic microfluidic device. Proceedings of the National Academy of Sciences of the United States of America. 2012; 109(3): 690-5.
Schwarzenberg J, Radu CG, Benz M, Fueger B, Tran AQ, Phelps ME, Witte ON, Satyamurthy N, Czernin J, Schiepers C Human biodistribution and radiation dosimetry of novel PET probes targeting the deoxyribonucleoside salvage pathway. Eur J Nucl Med Mol Imaging. 2010; 38(4): 711-21.
Graeber T G, Heath J R, Skaggs B J, Phelps M E, Remacle F, Levine R D Maximal entropy inference of oncogenicity from phosphorylation signaling. Proceedings of the National Academy of Sciences of the United States of America. 2010; 107(13): 6112-7.
Harki Daniel A, Satyamurthy Nagichettiar, Stout David B, Phelps Michael E, Dervan Peter B In vivo imaging of pyrrole-imidazole polyamides with positron emission tomography. Proceedings of the National Academy of Sciences of the United States of America. 2008; 105(35): 13039-44.
Weber Wolfgang A, Czernin Johannes, Phelps Michael E, Herschman Harvey R Technology Insight: novel imaging of molecular targets is an emerging area crucial to the development of targeted drugs. Nature clinical practice. Oncology. 2008; 5(1): 44-54.
Kepe Vladimir, Barrio Jorge R, Huang Sung-Cheng, Ercoli Linda, Siddarth Prabha, Shoghi-Jadid Kooresh, Cole Gregory M, Satyamurthy Nagichettiar, Cummings Jeffrey L, Small Gary W, Phelps Michael E Serotonin 1A receptors in the living brain of Alzheimer's disease patients. Proceedings of the National Academy of Sciences of the United States of America. 2006; 103(3): 702-7.
Filmont JE, Czernin J, Yap C, Silverman DH, Quon A, Phelps ME, Emmanouilides C Value of F-18 Fluorodeoxyglucose Positron Emission Tomography for Predicting the Clinical Outcome of Patients With Aggressive Lymphoma Prior to and After Autologous Stem-Cell Transplantation. Chest. 2003; 124(2): 608-613.
Liang Q, Nguyen K, Satyamurthy N, Barrio JR, Phelps ME, Gambhir SS, Herschman HR Monitoring adenoviral DNA delivery, using a mutant herpes simplex virus type 1 thymidine kinase gene as a PET reporter gene. Gene Ther. 2002; 9(24): 1659-1666.
Seltzer MA, Yap C, Silverman DH, Meta J, Schiepers C, Phelps ME, Sayre J, Ariannejad M, Gambhir SS, Rao J, Valk PE, Czernin J The impact of positron emission tomography on the management of patients with lung cancer: the referring physician's perspective. J Nucl Med. 2002; 43(6): 752-756.
Silverman DH, Small GW, Chang C, Lu CS, Kung de Auburto M, Chen W, Czernin J, Rapoport SI, Pietrini P, Alexander GE, Schapiro MB, Jagust WJ, Hoffman J, Welsh-Bohmer K, Alavi A, Clark CM, Salmon E, deLeon M, Mielke R, Cummings J, Kowell A, Gambhir SS, Hoh CK, Phelps ME Positron emission tomography in evaluation of dementia: regional brain metabolism and long term outcome. J Amer Med Assoc 2001; 286: 2120-2127.
Gambhir S S, Bauer E, Black M E, Liang Q, Kokoris M S, Barrio J R, Iyer M, Namavari M, Phelps M E, Herschman H R A mutant herpes simplex virus type 1 thymidine kinase reporter gene shows improved sensitivity for imaging reporter gene expression with positron emission tomography. Proceedings of the National Academy of Sciences of the United States of America. 2000; 97(6): 2785-90.
Phelps ME Positron emission tomography provides molecular imaging of biological processes. Proc Nat Acad Sci 2000; 97: 9226-9233.
Chatziioannou A F, Cherry S R, Shao Y, Silverman R W, Meadors K, Farquhar T H, Pedarsani M, Phelps M E Performance evaluation of microPET: a high-resolution lutetium oxyorthosilicate PET scanner for animal imaging. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 1999; 40(7): 1164-75.
Guerrero TM, Hoffman EJ, Dahlbom M, Cutler PD, Hawkins RA, Phelps ME Characterization of a whole body imaging technique for PET. IEEE 1990; 37: 676-680.
Mazziotta J C, Phelps M E, Pahl J J, Huang S C, Baxter L R, Riege W H, Hoffman J M, Kuhl D E, Lanto A B, Wapenski J A Reduced cerebral glucose metabolism in asymptomatic subjects at risk for Huntington's disease. The New England journal of medicine. 1987; 316(7): 357-62.
Chugani HT, Phelps ME Maturational changes in cerebral function in human infants determined by 18FDG positron emission tomography. Science 1986; 231: 840-843.
Phelps ME, Kuhl DE, Mazziotta JC Metabolic mapping of the brain's response to visual stimulation: studies in man. Science (cover article) 1981; 211: 1445-1448.
Phelps ME, Huang SC, Hoffman EJ, Selin CE, Kuhl DE Tomographic measurement of local cerebral glucose metabolic rate in man with (18F) fluorodeoxyglucose:Validation of method. Ann Neurol 1979; 6: 371-388.
Phelps ME, Hoffman EJ, Huang SC, Kuhl DE ECAT: A new computerized tomographic imaging system for positron-emitting radiopharmaceuticals. J Nucl Med 1978; 19: 635-647.
Phelps ME, Hoffman EJ, Mullani NA, Higgins CS, Ter-Pogossian MM Design considerations for a positron emission transaxial tomograph (PETT III). IEEE Nucl Sci 1976; NS-23: 516-522.
Phelps ME, Hoffman EJ, Mullani NA, Ter-Pogossian MM Application of annihilation coincidence detection to transaxial reconstruction tomography. J Nucl Med 1975; 16: 210-224.
Benz Matthias R, Czernin Johannes, Allen-Auerbach Martin S, Tap William D, Dry Sarah M, Elashoff David, Chow Kira, Evilevitch Vladimir, Eckardt Jeff J, Phelps Michael E, Weber Wolfgang A, Eilber Fritz C FDG-PET/CT imaging predicts histopathologic treatment responses after the initial cycle of neoadjuvant chemotherapy in high-grade soft-tissue sarcomas. Clinical cancer research : an official journal of the American Association for Cancer Research. 2009; 15(8): 2856-63.
Laing Rachel E, Walter Martin A, Campbell Dean O, Herschman Harvey R, Satyamurthy Nagichettiar, Phelps Michael E, Czernin Johannes, Witte Owen N, Radu Caius G Noninvasive prediction of tumor responses to gemcitabine using positron emission tomography. Proceedings of the National Academy of Sciences of the United States of America. 2009; 106(8): 2847-52.
Shu Chengyi J, Radu Caius G, Shelly Stephanie M, Vo Dan D, Prins Robert, Ribas Antoni, Phelps Michael E, Witte Owen N Quantitative PET reporter gene imaging of CD8+ T cells specific for a melanoma-expressed self-antigen. International immunology. 2009; 21(2): 155-65.
Small Gary W, Siddarth Prabha, Burggren Alison C, Kepe Vladimir, Ercoli Linda M, Miller Karen J, Lavretsky Helen, Thompson Paul M, Cole Greg M, Huang S C, Phelps Michael E, Bookheimer Susan Y, Barrio Jorge R Influence of cognitive status, age, and APOE-4 genetic risk on brain FDDNP positron-emission tomography imaging in persons without dementia. Archives of general psychiatry. 2009; 66(1): 81-7.
Small Gary W, Siddarth Prabha, Silverman Daniel H S, Ercoli Linda M, Miller Karen J, Lavretsky Helen, Bookheimer Susan Y, Huang S-C, Barrio Jorge R, Phelps Michael E Cognitive and cerebral metabolic effects of celecoxib versus placebo in people with age-related memory loss: randomized controlled study. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. 2008; 16(12): 999-1009.
Wei Liu H, Olafsen Tove, Radu Caius, Hildebrandt Isabel J, McCoy Mark R, Phelps Michael E, Meares Claude, Wu Anna M, Czernin Johannes, Weber Wolfgang A Engineered antibody fragments with infinite affinity as reporter genes for PET imaging. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2008; 49(11): 1828-35.
Kesner Adam L, Hsueh Wei-Ann, Czernin Johannes, Padgett Henry, Phelps Michael E, Silverman Daniel H S Radiation dose estimates for [18F]5-fluorouracil derived from PET-based and tissue-based methods in rats. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging. 2008; 10(6): 341-8.
Benz Matthias R, Allen-Auerbach Martin S, Eilber Fritz C, Chen Hui J J, Dry Sarah, Phelps Michael E, Czernin Johannes, Weber Wolfgang A Combined assessment of metabolic and volumetric changes for assessment of tumor response in patients with soft-tissue sarcomas. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2008; 49(10): 1579-84.
Burton Jeremy B, Johnson Mai, Sato Makoto, Koh Sok Boon S, Mulholland David J, Stout David, Chatziioannou Arion F, Phelps Michael E, Wu Hong, Wu Lily Adenovirus-mediated gene expression imaging to directly detect sentinel lymph node metastasis of prostate cancer. Nature medicine. 2008; 14(8): 882-8.
Benz Matthias R, Evilevitch Vladimir, Allen-Auerbach Martin S, Eilber Fritz C, Phelps Michael E, Czernin Johannes, Weber Wolfgang A Treatment monitoring by 18F-FDG PET/CT in patients with sarcomas: interobserver variability of quantitative parameters in treatment-induced changes in histopathologically responding and nonresponding tumors. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2008; 49(7): 1038-46.
Radu Caius G, Shu Chengyi J, Nair-Gill Evan, Shelly Stephanie M, Barrio Jorge R, Satyamurthy Nagichettiar, Phelps Michael E, Witte Owen N Molecular imaging of lymphoid organs and immune activation by positron emission tomography with a new [18F]-labeled 2'-deoxycytidine analog. Nature medicine. 2008; 14(7): 783-8.
Wei Liu Hua, Su Helen, Hildebrandt Isabel J, Phelps Michael E, Czernin Johannes, Weber Wolfgang A Changes in tumor metabolism as readout for Mammalian target of rapamycin kinase inhibition by rapamycin in glioblastoma. Clinical cancer research : an official journal of the American Association for Cancer Research. 2008; 14(11): 3416-26.
Su Helen, Seimbille Yann, Ferl Gregory Z, Bodenstein Claudia, Fueger Barbara, Kim Kevin J, Hsu Yu-Tien, Dubinett Steven M, Phelps Michael E, Czernin Johannes, Weber Wolfgang A Evaluation of [(18)F]gefitinib as a molecular imaging probe for the assessment of the epidermal growth factor receptor status in malignant tumors. European journal of nuclear medicine and molecular imaging. 2008; 35(6): 1089-99.
Evilevitch Vladimir, Weber Wolfgang A, Tap William D, Allen-Auerbach Martin, Chow Kira, Nelson Scott D, Eilber Fredrick R, Eckardt Jeffery J, Elashoff Robert M, Phelps Michael E, Czernin Johannes, Eilber Fritz C Reduction of glucose metabolic activity is more accurate than change in size at predicting histopathologic response to neoadjuvant therapy in high-grade soft-tissue sarcomas. Clinical cancer research : an official journal of the American Association for Cancer Research. 2008; 14(3): 715-20.
Chen Wei, Delaloye Sibylle, Silverman Daniel H S, Geist Cheri, Czernin Johannes, Sayre James, Satyamurthy Nagichettiar, Pope Whitney, Lai Albert, Phelps Michael E, Cloughesy Timothy Predicting treatment response of malignant gliomas to bevacizumab and irinotecan by imaging proliferation with [18F] fluorothymidine positron emission tomography: a pilot study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2007; 25(30): 4714-21.
Kesner Amanda L, Hsueh Wei-Ann, Htet Nwe Linn, Pio Betty S, Czernin Johannes, Pegram Mark D, Phelps Michael E, Silverman Daniel H S Biodistribution and predictive value of 18F-fluorocyclophosphamide in mice bearing human breast cancer xenografts. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2007; 48(12): 2021-7.
Saxe Jonathan P, Wu Hao, Kelly Theresa K, Phelps Michael E, Sun Yi E, Kornblum Harley I, Huang Jing A phenotypic small-molecule screen identifies an orphan ligand-receptor pair that regulates neural stem cell differentiation. Chemistry & biology. 2007; 14(9): 1019-30.
Silverman Daniel H S, Dy Christine J, Castellon Steven A, Lai Jasmine, Pio Betty S, Abraham Laura, Waddell Kari, Petersen Laura, Phelps Michael E, Ganz Patricia A Altered frontocortical, cerebellar, and basal ganglia activity in adjuvant-treated breast cancer survivors 5-10 years after chemotherapy. Breast cancer research and treatment. 2007; 103(3): 303-11.
Weber Wolfgang A, Czernin Johannes, Phelps Michael E Prognostic significance of fluorodeoxyglucose uptake in non-small cell lung cancer. A blurry picture?. Clinical cancer research : an official journal of the American Association for Cancer Research. 2007; 13(11): 3105-6.
Wu Hsiao-Ming, Sui Guodong, Lee Cheng-Chung, Prins Mayumi L, Ladno Waldemar, Lin Hong-Dun, Yu Amy S, Phelps Michael E, Huang Sung-Cheng In vivo quantitation of glucose metabolism in mice using small-animal PET and a microfluidic device. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2007; 48(5): 837-45.
Lin Tina W, de Aburto Michelle A Kung, Dahlbom Magnus, Huang Lynn L, Marvi Michael M, Tang Michael, Czernin Johannes, Phelps Michael E, Silverman Daniel H S Predicting seizure-free status for temporal lobe epilepsy patients undergoing surgery: prognostic value of quantifying maximal metabolic asymmetry extending over a specified proportion of the temporal lobe. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2007; 48(5): 776-82.
Radu Caius G, Shu Chengyi J, Shelly Stephanie M, Phelps Michael E, Witte Owen N Positron emission tomography with computed tomography imaging of neuroinflammation in experimental autoimmune encephalomyelitis. Proceedings of the National Academy of Sciences of the United States of America. 2007; 104(6): 1937-42.
Small Gary W, Kepe Vladimir, Ercoli Linda M, Siddarth Prabha, Bookheimer Susan Y, Miller Karen J, Lavretsky Helen, Burggren Alison C, Cole Greg M, Vinters Harry V, Thompson Paul M, Huang S-C, Satyamurthy N, Phelps Michael E, Barrio Jorge R PET of brain amyloid and tau in mild cognitive impairment. The New England journal of medicine. 2006; 355(25): 2652-63.
Hsueh Wei-Ann, Kesner Amanda L, Gangloff Anne, Pegram Mark D, Beryt Malgorzata, Czernin Johannes, Phelps Michael E, Silverman Daniel H S Predicting chemotherapy response to paclitaxel with 18F-Fluoropaclitaxel and PET. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2006; 47(12): 1995-9.
Kamata Masakazu, Wu Raymond P, An Dong Sung, Saxe Jonathan P, Damoiseaux Robert, Phelps Michael E, Huang Jing, Chen Irvin S Y Cell-based chemical genetic screen identifies damnacanthal as an inhibitor of HIV-1 Vpr induced cell death. Biochemical and biophysical research communications. 2006; 348(3): 1101-6.
Su Helen, Bodenstein Claudia, Dumont Rebecca A, Seimbille Yann, Dubinett Steven, Phelps Michael E, Herschman Harvey, Czernin Johannes, Weber Wolfgang Monitoring tumor glucose utilization by positron emission tomography for the prediction of treatment response to epidermal growth factor receptor kinase inhibitors. Clinical cancer research : an official journal of the American Association for Cancer Research. 2006; 12(19): 5659-67.
Wang Jinyi, Sui Guodong, Mocharla Vani P, Lin Rachel J, Phelps Michael E, Kolb Hartmuth C, Tseng Hsian-Rong Integrated microfluidics for parallel screening of an in situ click chemistry library. Angewandte Chemie (International ed. in English). 2006; 45(32): 5276-81.
Lu Yuxin, Dang Hoa, Middleton Blake, Zhang Zesong, Washburn Lorraine, Stout David B, Campbell-Thompson Martha, Atkinson Mark A, Phelps Michael, Gambhir Sanjiv Sam, Tian Jide, Kaufman Daniel L Noninvasive imaging of islet grafts using positron-emission tomography. Proceedings of the National Academy of Sciences of the United States of America. 2006; 103(30): 11294-9.
Small Gary W, Silverman Daniel H S, Siddarth Prabha, Ercoli Linda M, Miller Karen J, Lavretsky Helen, Wright Benjamin C, Bookheimer Susan Y, Barrio Jorge R, Phelps Michael E Effects of a 14-day healthy longevity lifestyle program on cognition and brain function. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. 2006; 14(6): 538-45.
Fueger Barbara J, Czernin Johannes, Hildebrandt Isabel, Tran Chris, Halpern Benjamin S, Stout David, Phelps Michael E, Weber Wolfgang A Impact of animal handling on the results of 18F-FDG PET studies in mice. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2006; 47(6): 999-1006.
Ercoli Linda, Siddarth Prabha, Huang Sung-Cheng, Miller Karen, Bookheimer Susan Y, Wright Benjamin C, Phelps Michael E, Small Gary Perceived loss of memory ability and cerebral metabolic decline in persons with the apolipoprotein E-IV genetic risk for Alzheimer disease. Archives of general psychiatry. 2006; 63(4): 442-8.
Allen-Auerbach Martin, Yeom Kristen, Park John, Phelps Michael, Czernin Johannes Standard PET/CT of the chest during shallow breathing is inadequate for comprehensive staging of lung cancer. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2006; 47(2): 298-301.
Yap Cecelia S, Czernin Johannes, Fishbein Michael C, Cameron Robert B, Schiepers Christiaan, Phelps Michael E, Weber Wolfgang A Evaluation of thoracic tumors with 18F-fluorothymidine and 18F-fluorodeoxyglucose-positron emission tomography. Chest. 2006; 129(2): 393-401.
Pio Betty S, Park Cecilia K, Pietras Richard, Hsueh Wei-Ann, Satyamurthy Nagichettiar, Pegram Mark D, Czernin Johannes, Phelps Michael E, Silverman Daniel H S Usefulness of 3'-[F-18]fluoro-3'-deoxythymidine with positron emission tomography in predicting breast cancer response to therapy. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging. 2006; 8(1): 36-42.
Lee Chung-Cheng, Sui Guodong, Elizarov Arkadij, Shu Chengyi Jenny, Shin Young-Shik, Dooley Alek N, Huang Jiang, Daridon Antoine, Wyatt Paul, Stout David, Kolb Hartmuth C, Witte Owen N, Satyamurthy Nagichettiar, Heath James R, Phelps Michael E, Quake Stephen R, Tseng Hsian-Rong Multistep synthesis of a radiolabeled imaging probe using integrated microfluidics. Science (New York, N.Y.). 2005; 310(5755): 1793-6.
Toyokuni Tatsushi, Kumar J S Dileep, Walsh Joseph C, Shapiro Alan, Talley John J, Phelps Michael E, Herschman Harvey R, Barrio Jorge R, Satyamurthy Nagichettiar Synthesis of 4-(5-[18F]fluoromethyl-3-phenylisoxazol-4-yl)benzenesulfonamide, a new [18F]fluorinated analogue of valdecoxib, as a potential radiotracer for imaging cyclooxygenase-2 with positron emission tomography. Bioorganic & medicinal chemistry letters. 2005; 15(21): 4699-702.
Gangloff Anne, Hsueh Wei-Ann, Kesner Amanda L, Kiesewetter Dale O, Pio Betty S, Pegram Mark D, Beryt Malgorzata, Townsend Allison, Czernin Johannes, Phelps Michael E, Silverman Daniel H S Estimation of paclitaxel biodistribution and uptake in human-derived xenografts in vivo with (18)F-fluoropaclitaxel. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2005; 46(11): 1866-71.
Stout David B, Chatziioannou Arion F, Lawson Timothy P, Silverman Robert W, Gambhir Sanjiv S, Phelps Michael E Small animal imaging center design: the facility at the UCLA Crump Institute for Molecular Imaging. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging. 2005; 7(6): 393-402.
Halpern Benjamin S, Schiepers Christiaan, Weber Wolfgang A, Crawford Tyler L, Fueger Barbara J, Phelps Michael E, Czernin Johannes Presurgical staging of non-small cell lung cancer: positron emission tomography, integrated positron emission tomography/CT, and software image fusion. Chest. 2005; 128(4): 2289-97.
Tran Amy, Pio Betty S, Khatibi Bahareh, Czernin Johannes, Phelps Michael E, Silverman Daniel H S 18F-FDG PET for staging breast cancer in patients with inner-quadrant versus outer-quadrant tumors: comparison with long-term clinical outcome. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2005; 46(9): 1455-9.
Huang Sung-Cheng, Truong David, Wu Hsiao-Ming, Chatziioannou Arion F, Shao Weber, Wu Anna M, Phelps Michael E An internet-based "kinetic imaging system" (KIS) for MicroPET. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging. 2005; 7(5): 330-41.
Fueger Barbara J, Weber Wolfgang A, Quon Andrew, Crawford Tyler L, Allen-Auerbach M S, Halpern B S, Ratib Osman, Phelps Michael E, Czernin Johannes Performance of 2-deoxy-2-[F-18]fluoro-D-glucose positron emission tomography and integrated PET/CT in restaged breast cancer patients. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging. 2005; 7(5): 369-76.
Peñuelas Iván, Mazzolini Guillermo, Boán José F, Sangro Bruno, Martí-Climent Josep, Ruiz María, Ruiz Juan, Satyamurthy Nagichettiar, Qian Cheng, Barrio Jorge R, Phelps Michael E, Richter José A, Gambhir Sanjiv S, Prieto Jesús Positron emission tomography imaging of adenoviral-mediated transgene expression in liver cancer patients. Gastroenterology. 2005; 128(7): 1787-95.
Palaskas Nicolaos, Larson Steven M, Schultz Nikolaus, Komisopoulou Evangelia, Wong Justin, Rohle Dan, Campos Carl, Yannuzzi Nicolas, Osborne Joseph R, Linkov Irina, Kastenhuber Edward R, Taschereau Richard, Plaisier Seema B, Tran Chris, Heguy Adriana, Wu Hong, Sander Chris, Phelps Michael E, Brennan Cameron, Port Elisa, Huse Jason T, Graeber Thomas G, Mellinghoff Ingo K 18F-fluorodeoxy-glucose positron emission tomography marks MYC-overexpressing human basal-like breast cancers. Cancer research. 2011; 71(15): 5164-74.
Chen Wei, Cloughesy Timothy, Kamdar Nirav, Satyamurthy Nagichettiar, Bergsneider Marvin, Liau Linda, Mischel Paul, Czernin Johannes, Phelps Michael E, Silverman Daniel H S Imaging proliferation in brain tumors with 18F-FLT PET: comparison with 18F-FDG. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2005; 46(6): 945-52.
Liu Kan, Lepin Eric J, Wang Ming-Wei, Guo Feng, Lin Wei-Yu, Chen Yi-Chun, Sirk Shannon J, Olma Sebastian, Phelps Michael E, Zhao Xing-Zhong, Tseng Hsian-Rong, Michael van Dam R, Wu Anna M, Shen Clifton K-F Microfluidic-based 18F-labeling of biomolecules for immuno-positron emission tomography. Molecular imaging. 2011; 10(3): 168-76, 1-7.
Shoghi-Jadid Kooresh, Barrio Jorge R, Kepe Vladimir, Wu Hsiao-Ming, Small Gary W, Phelps Michael E, Huang Sung-Cheng Imaging beta-amyloid fibrils in Alzheimer's disease: a critical analysis through simulation of amyloid fibril polymerization. Nuclear medicine and biology. 2005; 32(4): 337-51.
Schwarzenberg Johannes, Radu Caius G, Benz Matthias, Fueger Barbara, Tran Andrew Q, Phelps Michael E, Witte Owen N, Satyamurthy Nagichettiar, Czernin Johannes, Schiepers Christiaan Human biodistribution and radiation dosimetry of novel PET probes targeting the deoxyribonucleoside salvage pathway. European journal of nuclear medicine and molecular imaging. 2011; 38(4): 711-21.
Kim Jong-Ho, Czernin Johannes, Allen-Auerbach Martin S, Halpern Benjamin S, Fueger Barbara J, Hecht Joel R, Ratib Osman, Phelps Michael E, Weber Wolfgang A Comparison between 18F-FDG PET, in-line PET/CT, and software fusion for restaging of recurrent colorectal cancer. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2005; 46(4): 587-95.
Walter Martin A, Benz Matthias R, Hildebrandt Isabel J, Laing Rachel E, Hartung Verena, Damoiseaux Robert D, Bockisch Andreas, Phelps Michael E, Czernin Johannes, Weber Wolfgang A Metabolic imaging allows early prediction of response to vandetanib. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2011; 52(2): 231-40.
Yaghoubi Shahriar S, Barrio Jorge R, Namavari Mohammad, Satyamurthy Nagichettiar, Phelps Michael E, Herschman Harvey R, Gambhir Sanjiv S Imaging progress of herpes simplex virus type 1 thymidine kinase suicide gene therapy in living subjects with positron emission tomography. Cancer gene therapy. 2005; 12(3): 329-39.
Shin Jonghan, Kepe Vladimir, Small Gary W, Phelps Michael E, Barrio Jorge R Multimodal Imaging of Alzheimer Pathophysiology in the Brain's Default Mode Network. International journal of Alzheimer's disease. 2011; 2011(2): 687945.
Rasgon Natalie L, Silverman Daniel, Siddarth Prabha, Miller Karen, Ercoli Linda M, Elman Shana, Lavretsky Helen, Huang S-C, Phelps Michael E, Small Gary W Estrogen use and brain metabolic change in postmenopausal women. Neurobiology of aging. 2005; 26(2): 229-35.
Fang Cong, Wang Yanju, Vu Nam T, Lin Wei-Yu, Hsieh Yao-Te, Rubbi Liudmilla, Phelps Michael E, Müschen Markus, Kim Yong-Mi, Chatziioannou Arion F, Tseng Hsian-Rong, Graeber Thomas G Integrated microfluidic and imaging platform for a kinase activity radioassay to analyze minute patient cancer samples. Cancer research. 2010; 70(21): 8299-308.
Waldherr Christian, Mellinghoff Ingo K, Tran Chris, Halpern Benjamin S, Rozengurt Nora, Safaei Arash, Weber Wolfgang A, Stout David, Satyamurthy Nagichettiar, Barrio Jorge, Phelps Michael E, Silverman Daniel H, Sawyers Charles L, Czernin Johannes Monitoring antiproliferative responses to kinase inhibitor therapy in mice with 3'-deoxy-3'-18F-fluorothymidine PET. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2005; 46(1): 114-20.
Phelps Michael E, Barrio Jorge R Correlation of brain amyloid with "aerobic glycolysis": A question of assumptions?. Proceedings of the National Academy of Sciences of the United States of America. 2010; 107(41): 17459-60.
Allen-Auerbach Martin, Quon Andrew, Weber Wolfgang A, Obrzut Sebastian, Crawford Tyler, Silverman Daniel H S, Ratib Osman, Phelps Michael E, Czernin Johannes Comparison between 2-deoxy-2-[18F]fluoro-D-glucose positron emission tomography and positron emission tomography/computed tomography hardware fusion for staging of patients with lymphoma. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging. 2005; 6(6): 411-6.
Fueger Barbara J, Czernin Johannes, Cloughesy Timothy, Silverman Daniel H, Geist Cheri L, Walter Martin A, Schiepers Christiaan, Nghiemphu Phioanh, Lai Albert, Phelps Michael E, Chen Wei Correlation of 6-18F-fluoro-L-dopa PET uptake with proliferation and tumor grade in newly diagnosed and recurrent gliomas. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2010; 51(10): 1532-8.
Phelps Michael In tribute of Edward J. Hoffman, PhD (1942-2004). Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging. 2004; 6(5): 271-4.
Hood Leroy, Heath James R, Phelps Michael E, Lin Biaoyang Systems biology and new technologies enable predictive and preventative medicine. Science (New York, N.Y.). 2004; 306(5696): 640-3.
Austin Wayne R, Armijo Amanda L, Campbell Dean O, Singh Arun S, Hsieh Terry, Nathanson David, Herschman Harvey R, Phelps Michael E, Witte Owen N, Czernin Johannes, Radu Caius G Nucleoside salvage pathway kinases regulate hematopoiesis by linking nucleotide metabolism with replication stress. The Journal of experimental medicine. 2012; 209(12): 2215-28.
Sun Jing, Masterman-Smith Michael D, Graham Nicholas A, Jiao Jing, Mottahedeh Jack, Laks Dan R, Ohashi Minori, DeJesus Jason, Kamei Ken-ichiro, Lee Ki-Bum, Wang Hao, Yu Zeta T F, Lu Yi-Tsung, Hou Shuang, Li Keyu, Liu Max, Zhang Nangang, Wang Shutao, Angenieux Brigitte, Panosyan Eduard, Samuels Eric R, Park Jun, Williams Dirk, Konkankit Vera, Nathanson David, van Dam R Michael, Phelps Michael E, Wu Hong, Liau Linda M, Mischel Paul S, Lazareff Jorge A, Kornblum Harley I, Yong William H, Graeber Thomas G, Tseng Hsian-Rong A microfluidic platform for systems pathology: multiparameter single-cell signaling measurements of clinical brain tumor specimens. Cancer research. 2010; 70(15): 6128-38.
Seltzer Marc A, Jahan Shamim A, Sparks Richard, Stout David B, Satyamurthy Nagichettiar, Dahlbom Magnus, Phelps Michael E, Barrio Jorge R Radiation dose estimates in humans for (11)C-acetate whole-body PET. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2004; 45(7): 1233-6.
Harris Robert J, Cloughesy Timothy F, Pope Whitney B, Nghiemphu Phioanh L, Lai Albert, Zaw Taryar, Czernin Johannes, Phelps Michael E, Chen Wei, Ellingson Benjamin M 18F-FDOPA and 18F-FLT positron emission tomography parametric response maps predict response in recurrent malignant gliomas treated with bevacizumab. Neuro-oncology. 2012; 14(8): 1079-89.
Benz Matthias R, Dry Sarah M, Eilber Fritz C, Allen-Auerbach Martin S, Tap William D, Elashoff David, Phelps Michael E, Czernin Johannes Correlation between glycolytic phenotype and tumor grade in soft-tissue sarcomas by 18F-FDG PET. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2010; 51(8): 1174-81.
Walter Martin A, Hildebrandt Isabel J, Hacke Katrin, Kesner Adam L, Kelly Owen, Lawson Gregory W, Phelps Michael E, Czernin Johannes, Weber Wolfgang A, Schiestl Robert H Small-animal PET/CT for monitoring the development and response to chemotherapy of thymic lymphoma in Trp53-/- mice. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2010; 51(8): 1285-92.
Hattori Naoya, Huang Sung-Cheng, Wu Hsiao-Ming, Liao Weihsun, Glenn Thomas C, Vespa Paul M, Phelps Michael E, Hovda David A, Bergsneider Marvin Acute changes in regional cerebral (18)F-FDG kinetics in patients with traumatic brain injury. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2004; 45(5): 775-83.
Herrmann Ken, Benz Matthias R, Czernin Johannes, Allen-Auerbach Martin S, Tap William D, Dry Sarah M, Schuster Tibor, Eckardt Jeff J, Phelps Michael E, Weber Wolfgang A, Eilber Fritz C 18F-FDG-PET/CT Imaging as an early survival predictor in patients with primary high-grade soft tissue sarcomas undergoing neoadjuvant therapy. Clinical cancer research : an official journal of the American Association for Cancer Research. 2012; 18(7): 2024-31.
Shu Chengyi J, Campbell Dean O, Lee Jason T, Tran Andrew Q, Wengrod Jordan C, Witte Owen N, Phelps Michael E, Satyamurthy Nagichettiar, Czernin Johannes, Radu Caius G Novel PET probes specific for deoxycytidine kinase. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2010; 51(7): 1092-8.
Hattori Naoya, Bergsneider Marvin, Wu Hsiao-Ming, Glenn Thomas C, Vespa Paul M, Hovda David A, Phelps Michael E, Huang Sung-Cheng Accuracy of a method using short inhalation of (15)O-O(2) for measuring cerebral oxygen extraction fraction with PET in healthy humans. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2004; 45(5): 765-70.
Walter Franziska, Cloughesy Timothy, Walter Martin A, Lai Albert, Nghiemphu Phioanh, Wagle Naveed, Fueger Barbara, Satyamurthy Nagichettiar, Phelps Michael E, Czernin Johannes Impact of 3,4-dihydroxy-6-18F-fluoro-L-phenylalanine PET/CT on managing patients with brain tumors: the referring physician's perspective. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2012; 53(3): 393-8.
Schiepers Christiaan, Dahlbom Magnus, Chen Wei, Cloughesy Timothy, Czernin Johannes, Phelps Michael E, Huang Sung-Cheng Kinetics of 3'-deoxy-3'-18F-fluorothymidine during treatment monitoring of recurrent high-grade glioma. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2010; 51(5): 720-7.
Cummings Jeffrey L, Silverman Dan, Small Gary, Phelps Michael The role of positron emission tomography in the diagnosis of Alzheimer's disease. Journal of the American Geriatrics Society. 2004; 52(3): 467-8; author reply 468-9.
Schwarzenberg Johannes, Czernin Johannes, Cloughesy Timothy F, Ellingson Benjamin M, Pope Whitney B, Geist Cheri, Dahlbom Magnus, Silverman Daniel H S, Satyamurthy Nagichettiar, Phelps Michael E, Chen Wei 3'-deoxy-3'-18F-fluorothymidine PET and MRI for early survival predictions in patients with recurrent malignant glioma treated with bevacizumab. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2012; 53(1): 29-36.
Brewer Sarah, Nair-Gill Evan, Wei Bo, Chen Ling, Li Xiaoxiao, Riedinger Mireille, Campbell Dean O, Wiltzius Stephanie, Satyamurthy Nagichettiar, Phelps Michael E, Radu Caius, Witte Owen N, Braun Jonathan Epithelial uptake of [18F]1-(2'-deoxy-2'-arabinofuranosyl) cytosine indicates intestinal inflammation in mice. Gastroenterology. 2010; 138(4): 1266-75.
Wu Hsiao-Ming, Huang Sung-Cheng, Hattori Naoya, Glenn Thomas C, Vespa Paul M, Yu Chin-Lung, Hovda David A, Phelps Michael E, Bergsneider Marvin Selective metabolic reduction in gray matter acutely following human traumatic brain injury. Journal of neurotrauma. 2004; 21(2): 149-61.
Benz Matthias R, Herrmann Ken, Walter Franziska, Garon Edward B, Reckamp Karen L, Figlin Robert, Phelps Michael E, Weber Wolfgang A, Czernin Johannes, Allen-Auerbach Martin S (18)F-FDG PET/CT for monitoring treatment responses to the epidermal growth factor receptor inhibitor erlotinib. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2011; 52(11): 1684-9.
Apostolova Liana G, Thompson Paul M, Rogers Steve A, Dinov Ivo D, Zoumalan Charleen, Steiner Calen A, Siu Erin, Green Amity E, Small Gary W, Toga Arthur W, Cummings Jeffrey L, Phelps Michael E, Silverman Daniel H Surface feature-guided mapping of cerebral metabolic changes in cognitively normal and mildly impaired elderly. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging. 2010; 12(2): 218-24.
Filmont Jean-Emmanuel, Yap Cecelia S, Ko Fred, Vranjesevic Duska, Quon Andrew, Margolis Daniel J A, Safaei Arash, Emmanouilides Christos, Silverman Daniel H S, Phelps Michael E, Czernin Johannes Conventional imaging and 2-deoxy-2-[(18)F]fluoro-D-glucose positron emission tomography for predicting the clinical outcome of patients with previously treated Hodgkin's disease. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging. 2004; 6(1): 47-54.
Wardak Mirwais, Schiepers Christiaan, Dahlbom Magnus, Cloughesy Timothy, Chen Wei, Satyamurthy Nagichettiar, Czernin Johannes, Phelps Michael E, Huang Sung-Cheng Discriminant analysis of ¹⁸F-fluorothymidine kinetic parameters to predict survival in patients with recurrent high-grade glioma. Clinical cancer research : an official journal of the American Association for Cancer Research. 2011; 17(20): 6553-62.
Toy Gerald, Austin Wayne R, Liao Hsiang-I, Cheng Donghui, Singh Arun, Campbell Dean O, Ishikawa Tomo-o, Lehmann Lynn W, Satyamurthy Nagichettiar, Phelps Michael E, Herschman Harvey R, Czernin Johannes, Witte Owen N, Radu Caius G Requirement for deoxycytidine kinase in T and B lymphocyte development. Proceedings of the National Academy of Sciences of the United States of America. 2010; 107(12): 5551-6.
Walter Franziska, Federman Noah, Apichairuk Wipapat, Nelson Scott, Phelps Michael E, Allen-Auerbach Martin, Walter Martin A, Czernin Johannes 18F-fluorodeoxyglucose uptake of bone and soft tissue sarcomas in pediatric patients. Pediatric hematology and oncology. 2011; 28(7): 579-87.
Benz Matthias R, Czernin Johannes, Dry Sarah M, Tap William D, Allen-Auerbach Martin S, Elashoff David, Phelps Michael E, Weber Wolfgang A, Eilber Fritz C Quantitative F18-fluorodeoxyglucose positron emission tomography accurately characterizes peripheral nerve sheath tumors as malignant or benign. Cancer. 2010; 116(2): 451-8.
Benz Matthias R, Czernin Johannes, Tap William D, Eckardt Jeffrey J, Seeger Leanne L, Allen-Auerbach Martin S, Dry Sarah M, Phelps Michael E, Weber Wolfgang A, Eilber Fritz C FDG-PET/CT Imaging Predicts Histopathologic Treatment Responses after Neoadjuvant Therapy in Adult Primary Bone Sarcomas. Sarcoma. 2010; 2010(2): 143540.
Gregorian Caroline, Nakashima Jonathan, Dry Sarah M, Nghiemphu P Leia, Smith Kate Barzan, Ao Yan, Dang Julie, Lawson Gregory, Mellinghoff Ingo K, Mischel Paul S, Phelps Michael, Parada Luis F, Liu Xin, Sofroniew Michael V, Eilber Fritz C, Wu Hong PTEN dosage is essential for neurofibroma development and malignant transformation. Proceedings of the National Academy of Sciences of the United States of America. 2009; 106(46): 19479-84.
Wang Yanju, Lin Wei-Yu, Liu Kan, Lin Rachel J, Selke Matthias, Kolb Hartmuth C, Zhang Nangang, Zhao Xing-Zhong, Phelps Michael E, Shen Clifton K F, Faull Kym F, Tseng Hsian-Rong An integrated microfluidic device for large-scale in situ click chemistry screening. Lab on a chip. 2009; 9(16): 2281-5.
Guo Deliang, Hildebrandt Isabel J, Prins Robert M, Soto Horacio, Mazzotta Mary M, Dang Julie, Czernin Johannes, Shyy John Y-J, Watson Andrew D, Phelps Michael, Radu Caius G, Cloughesy Timothy F, Mischel Paul S The AMPK agonist AICAR inhibits the growth of EGFRvIII-expressing glioblastomas by inhibiting lipogenesis. Proceedings of the National Academy of Sciences of the United States of America. 2009; 106(31): 12932-7.
Fueger Barbara J, Yeom Kristen, Czernin Johannes, Sayre James W, Phelps Michael E, Allen-Auerbach Martin S Comparison of CT, PET, and PET/CT for staging of patients with indolent non-Hodgkin's lymphoma. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging. 2009; 11(4): 269-74.
Yu Amy S, Lin Hong-Dun, Huang Sung-Cheng, Phelps Michael E, Wu Hsiao-Ming Quantification of cerebral glucose metabolic rate in mice using 18F-FDG and small-animal PET. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2009; 50(6): 966-73.
Ercoli Linda M, Siddarth Prabha, Kepe Vladimir, Miller Karen J, Huang S-C, Cole Gregory M, Lavretsky Helen, Bookheimer Susan Y, Kim Jeanne, Phelps Michael E, Barrio Jorge R, Small Gary W Differential FDDNP PET patterns in nondemented middle-aged and older adults. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. 2009; 17(5): 397-406.