FACULTY RESEARCH

Faculty List

Harvey Roy Herschman, Ph.D.

Work Email Address: hherschman@mednet.ucla.edu

Fax Number: (310) 825-1447

Office Phone Number: (310) 825-8735
(310) 825-8745

Office Address:
341 Boyer Hall (MBI), 611 Charles E. Young Drive East
Los Angeles, CA 90095

Department / Division Affiliations
Distinguished Research Professor, Biological Chemistry
Distinguished Professor, and Vice Chair, Molecular & Medical Pharmacology
Member, CTSI, Crump Institute for Molecular Imaging, JCCC Cancer Molecular Imaging, Molecular Biology Institute, Molecular Pharmacology GPB Home Area
Faculty, Molecular Biology IDP

Research Interests
We study how extracellular stimuli elicit changes in cell growth and differentiation, as a result of induced transcription of "primary response" genes. One gene we discovered encodes a second form of cyclooxygenase (COX-2), the rate limiting enzyme in prostaglandin production and the target of a new generation of anti-inflammatory, anti-pyretic and analgesic pharmaceutical agents. We also identified synaptotagmin 4 as a depolarization-induced neuronal gene; a candidate for a mediator of depolarization-induced synaptic plasticity. Lastly, we have merged principles of cell biology, molecular biology and molecular imaging technologies to develop procedures that repetitively, non-invasively and quantitatively image reporter gene expression in intact, living animals.


Publications
Gil Jose S, Machado Hidevaldo B, Campbell Dean O, McCracken Melissa, Radu Caius, Witte Owen N, Herschman Harvey R Application of a Rapid, Simple, and Accurate Adenovirus-Based Method to Compare PET Reporter Gene/PET Reporter Probe Systems. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging. 2013; 15(3): 273-81.
Herschman Harvey R, Czernin Johannes A spotlight from prostate cancer. Cancer discovery. 2012; 2(4): 301-3.
Li Hua-Jung, Reinhardt Ferenc, Herschman Harvey R, Weinberg Robert A Cancer-stimulated mesenchymal stem cells create a carcinoma stem cell niche via prostaglandin E2 signaling. Cancer discovery. 2012; 2(9): 840-55.
Hill Reginald, Li Yunfeng, Tran Linh M, Dry Sarah, Calvopina Joseph Hargan, Garcia Alejandro, Kim Christine, Wang Ying, Donahue Timothy R, Herschman Harvey R, Wu Hong Cell intrinsic role of COX-2 in pancreatic cancer development. Molecular cancer therapeutics. 2012; 11(10): 2127-37.
Austin Wayne R, Armijo Amanda L, Campbell Dean O, Singh Arun S, Hsieh Terry, Nathanson David, Herschman Harvey R, Phelps Michael E, Witte Owen N, Czernin Johannes, Radu Caius G Nucleoside salvage pathway kinases regulate hematopoiesis by linking nucleotide metabolism with replication stress. The Journal of experimental medicine. 2012; 209(12): 2215-28.
Campbell Dean O, Yaghoubi Shahriar S, Su Ying, Lee Jason T, Auerbach Martin S, Herschman Harvey, Satyamurthy Nagichettiar, Czernin Johannes, Lavie Arnon, Radu Caius G Structure-guided engineering of human thymidine kinase 2 as a positron emission tomography reporter gene for enhanced phosphorylation of non-natural thymidine analog reporter probe. The Journal of biological chemistry. 2012; 287(1): 446-54.
Gil Jose S, Machado Hidevaldo B, Herschman Harvey R A Method to Rapidly and Accurately Compare the Relative Efficacies of Non-invasive Imaging Reporter Genes in a Mouse Model and its Application to Luciferase Reporters. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging. 2011; .
Ishikawa Tomo-O, Oshima Masanobu, Herschman Harvey R Cox-2 deletion in myeloid and endothelial cells, but not in epithelial cells, exacerbates murine colitis. Carcinogenesis. 2011; 32(3): 417-26.
Zaiss Anne K, Lawrence Roger, Elashoff David, Esko Jeffrey D, Herschman Harvey R Differential effects of murine and human factor X on adenovirus transduction via cell-surface heparan sulfate. The Journal of biological chemistry. 2011; 286(28): 24535-43.
Lu Yujie, Machado Hidevaldo B, Bao Qinan, Stout David, Herschman Harvey, Chatziioannou Arion F In vivo mouse bioluminescence tomography with radionuclide-based imaging validation. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging. 2011; 13(1): 53-8.
Narasimha Ajay J, Watanabe Junji, Ishikawa Tomo-o, Priceman Saul J, Wu Lily, Herschman Harvey R, Reddy Srinivasa T Absence of myeloid COX-2 attenuates acute inflammation but does not influence development of atherosclerosis in apolipoprotein E null mice. Arteriosclerosis, thrombosis, and vascular biology. 2010; 30(2): 260-8.
Zhang Weizhou, Kater Arnon P, Widhopf George F, Chuang Han-Yu, Enzler Thomas, James Danelle F, Poustovoitov Maxim, Tseng Ping-Hui, Janz Siegfried, Hoh Carl, Herschman Harvey, Karin Michael, Kipps Thomas J B-cell activating factor and v-Myc myelocytomatosis viral oncogene homolog (c-Myc) influence progression of chronic lymphocytic leukemia. Proceedings of the National Academy of Sciences of the United States of America. 2010; 107(44): 18956-60.
Streicher John M, Kamei Kenichiro, Ishikawa Tomo-o, Herschman Harvey, Wang Yibin Compensatory hypertrophy induced by ventricular cardiomyocyte-specific COX-2 expression in mice. Journal of molecular and cellular cardiology. 2010; 49(1): 88-94.
Ishikawa Tomo-O, Herschman Harvey R Conditional Bicistronic Cre Reporter Line Expressing Both Firefly Luciferase and beta-galactosidase. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging. 2010; 298(6): .
Ishikawa Tomo-o, Jain Naveen K, Herschman Harvey R Cox-2 gene expression in chemically induced skin papillomas cannot predict subsequent tumor fate. Molecular oncology. 2010; 4(4): 347-56.
Tseng Han-Ching, Arasteh Aida, Paranjpe Avina, Teruel Antonia, Yang Wendy, Behel Armin, Alva Jackelyn A, Walter Gina, Head Christian, Ishikawa Tomo-o, Herschman Harvey R, Cacalano Nicholas, Pyle April D, Park No-Hee, Jewett Anahid Increased lysis of stem cells but not their differentiated cells by natural killer cells; de-differentiation or reprogramming activates NK cells. PloS one. 2010; 5(7): e11590.
Streicher John M, Ren Shuxun, Herschman Harvey, Wang Yibin MAPK-activated protein kinase-2 in cardiac hypertrophy and cyclooxygenase-2 regulation in heart. Circulation research. 2010; 106(8): 1434-43.
Watanabe Junji, Lin James A, Narasimha Ajay J, Shahbazian Ani, Ishikawa Tomo-O, Martin Martin G, Herschman Harvey R, Reddy Srinivasa T Novel anti-inflammatory functions for endothelial and myeloid cyclooxygenase-2 in a new mouse model of Crohn's disease. American journal of physiology. Gastrointestinal and liver physiology. 2010; 298(6): G842-50.
Huang Hechang, Chikazu Daichi, Voznesensky Olga S, Herschman Harvey R, Kream Barbara E, Drissi Hicham, Pilbeam Carol C Parathyroid hormone induction of cyclooxygenase-2 in murine osteoblasts: role of the calcium-calcineurin-NFAT pathway. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2010; 25(4): 819-29.
Ishikawa Tomo-O, Kumar Indracanti Prem, Machado Hidevaldo B, Wong Koon-Pong, Kusewitt Donna, Huang Sung-Cheng, Fischer Susan M, Herschman Harvey R Positron emission tomography imaging of DMBA/TPA mouse skin multi-step tumorigenesis. Molecular oncology. 2010; 4(2): 119-25.
Papanicolaou Kyriakos N, Streicher John M, Ishikawa Tomo-O, Herschman Harvey, Wang Yibin, Walsh Kenneth Preserved heart function and maintained response to cardiac stresses in a genetic model of cardiomyocyte-targeted deficiency of cyclooxygenase-2. Journal of molecular and cellular cardiology. 2010; 49(2): 196-209.
Toy Gerald, Austin Wayne R, Liao Hsiang-I, Cheng Donghui, Singh Arun, Campbell Dean O, Ishikawa Tomo-o, Lehmann Lynn W, Satyamurthy Nagichettiar, Phelps Michael E, Herschman Harvey R, Czernin Johannes, Witte Owen N, Radu Caius G Requirement for deoxycytidine kinase in T and B lymphocyte development. Proceedings of the National Academy of Sciences of the United States of America. 2010; 107(12): 5551-6.
Johnson Stuart L, Franz Christoph, Kuhn Stephanie, Furness David N, Rüttiger Lukas, Münkner Stefan, Rivolta Marcelo N, Seward Elizabeth P, Herschman Harvey R, Engel Jutta, Knipper Marlies, Marcotti Walter Synaptotagmin IV determines the linear Ca2+ dependence of vesicle fusion at auditory ribbon synapses. Nature neuroscience. 2010; 13(1): 45-52.
Ishikawa Tomo-O, Herschman Harvey R Tumor formation in a mouse model of colitis-associated colon cancer does not require COX-1 or COX-2 expression. Carcinogenesis. 2010; 31(4): 729-36.
Ohashi Koji, Ouchi Noriyuki, Sato Kaori, Higuchi Akiko, Ishikawa Tomo-o, Herschman Harvey R, Kihara Shinji, Walsh Kenneth Adiponectin promotes revascularization of ischemic muscle through a cyclooxygenase 2-dependent mechanism. Molecular and cellular biology. 2009; 29(13): 3487-99.
Li Hua-Jung, Everts Maaike, Yamamoto Masato, Curiel David T, Herschman Harvey R Combined transductional untargeting/retargeting and transcriptional restriction enhances adenovirus gene targeting and therapy for hepatic colorectal cancer tumors. Cancer research. 2009; 69(2): 554-64.
Lu Yujie, Machado Hidevaldo B, Douraghy Ali, Stout David, Herschman Harvey, Chatziioannou Arion F Experimental bioluminescence tomography with fully parallel radiative-transfer-based reconstruction framework. Optics express. 2009; 17(19): 16681-95.
Ishikawa Tomo-O, Jain Naveen, Herschman Harvey R Feedback regulation of cyclooxygenase-2 transcription ex vivo and in vivo. Biochemical and biophysical research communications. 2009; 378(3): 534-8.
Laing Rachel E, Walter Martin A, Campbell Dean O, Herschman Harvey R, Satyamurthy Nagichettiar, Phelps Michael E, Czernin Johannes, Witte Owen N, Radu Caius G Noninvasive prediction of tumor responses to gemcitabine using positron emission tomography. Proceedings of the National Academy of Sciences of the United States of America. 2009; 106(8): 2847-52.
Kenanova Vania, Barat Bhaswati, Olafsen Tove, Chatziioannou Arion, Herschman Harvey R, Braun Jonathan, Wu Anna M Recombinant carcinoembryonic antigen as a reporter gene for molecular imaging. European journal of nuclear medicine and molecular imaging. 2009; 36(1): 104-14.
Lu Yujie, Douraghy Ali, Machado Hidevaldo B, Stout David, Tian Jie, Herschman Harvey, Chatziioannou Arion F Spectrally resolved bioluminescence tomography with the third-order simplified spherical harmonics approximation. Physics in medicine and biology. 2009; 54(21): 6477-93.
Lomenick Brett, Hao Rui, Jonai Nao, Chin Randall M, Aghajan Mariam, Warburton Sarah, Wang Jianing, Wu Raymond P, Gomez Fernando, Loo Joseph A, Wohlschlegel James A, Vondriska Thomas M, Pelletier Jerry, Herschman Harvey R, Clardy Jon, Clarke Catherine F, Huang Jing Target identification using drug affinity responsive target stability (DARTS). Proceedings of the National Academy of Sciences of the United States of America. 2009; 106(51): 21984-9.
Zaiss Anne K, Machado Hidevaldo B, Herschman Harvey R The influence of innate and pre-existing immunity on adenovirus therapy. Journal of cellular biochemistry. 2009; 108(4): 778-90.
Jain Naveen K, Ishikawa Tomo-o, Spigelman Igor, Herschman Harvey R COX-2 expression and function in the hyperalgesic response to paw inflammation in mice. Prostaglandins, leukotrienes, and essential fatty acids. 2008; 79(6): 183-90.
Weber Wolfgang A, Czernin Johannes, Phelps Michael E, Herschman Harvey R Technology Insight: novel imaging of molecular targets is an emerging area crucial to the development of targeted drugs. Nature clinical practice. Oncology. 2008; 5(1): 44-54.
Machado Hidevaldo B, Vician Linda J, Herschman Harvey R The MAPK pathway is required for depolarization-induced . Journal of neuroscience research. 2008; 86(3): 593-602.
Sui Guodong, Lee Cheng-Chung, Kamei Ken-Ichiro, Li Hua-Jung, Wang Jin-Yi, Wang Jun, Herschman Harvey R, Tseng Hsian-Rong A microfluidic platform for sequential ligand labeling and cell binding analysis. Biomedical microdevices. 2007; 9(3): 301-5.
Li Hua-Jung, Everts Maaike, Pereboeva Larisa, Komarova Svetlana, Idan Anat, Curiel David T, Herschman Harvey R Adenovirus tumor targeting and hepatic untargeting by a coxsackie/adenovirus receptor ectodomain anti-carcinoembryonic antigen bispecific adapter. Cancer research. 2007; 67(11): 5354-61.
Su Feng, Kozak Katherine R, Herschman Harvey, Reddy Srinivasa T, Farias-Eisner Robin Characterization of the rat urokinase plasminogen activator receptor promoter in PC12 cells. Journal of neuroscience research. 2007; 85(9): 1952-8.
Koya Richard C, Kimura Takahiro, Ribas Antoni, Rozengurt Nora, Lawson Gregory W, Faure-Kumar Emmanuelle, Wang He-jing, Herschman Harvey, Kasahara Noriyuki, Stripecke Renata Lentiviral vector-mediated autonomous differentiation of mouse bone marrow cells into immunologically potent dendritic cell vaccines. Molecular therapy : the journal of the American Society of Gene Therapy. 2007; 15(5): 971-80.
Ishikawa Tomo-O, Griffin Kevin J P, Banerjee Utpal, Herschman Harvey R The zebrafish genome contains two inducible, functional cyclooxygenase-2 genes. Biochemical and biophysical research communications. 2007; 352(1): 181-7.
Ishikawa Tomo-o, Herschman Harvey R Two inducible, functional cyclooxygenase-2 genes are present in the rainbow trout genome. Journal of cellular biochemistry. 2007; 102(6): 1486-92.
Ishikawa Tomo-O, Herschman Harvey R Conditional knockout mouse for tissue-specific disruption of the cyclooxygenase-2 (Cox-2) gene. Genesis (New York, N.Y. : 2000). 2006; 44(3): 143-9.
Ishikawa Tomo-O, Jain Naveen K, Taketo Makoto M, Herschman Harvey R Imaging cyclooxygenase-2 (Cox-2) gene expression in living animals with a luciferase knock-in reporter gene. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging. 2006; 8(3): 171-87.
Czernin Johannes, Weber Wolfgang A, Herschman Harvey R Molecular imaging in the development of cancer therapeutics. Annual review of medicine. 2006; 57(3): 99-118.
Su Helen, Bodenstein Claudia, Dumont Rebecca A, Seimbille Yann, Dubinett Steven, Phelps Michael E, Herschman Harvey, Czernin Johannes, Weber Wolfgang Monitoring tumor glucose utilization by positron emission tomography for the prediction of treatment response to epidermal growth factor receptor kinase inhibitors. Clinical cancer research : an official journal of the American Association for Cancer Research. 2006; 12(19): 5659-67.
Xu Zheng, Choudhary Shilpa, Voznesensky Olga, Mehrotra Meenal, Woodard Monica, Hansen Marc, Herschman Harvey, Pilbeam Carol Overexpression of COX-2 in human osteosarcoma cells decreases proliferation and increases apoptosis. Cancer research. 2006; 66(13): 6657-64.
Lu Gang, Kang Young Jun, Han Jiahuai, Herschman Harvey R, Stefani Enrico, Wang Yibin TAB-1 modulates intracellular localization of p38 MAP kinase and downstream signaling. The Journal of biological chemistry. 2006; 281(9): 6087-95.
Kamei Ken-ichiro, Ishikawa Tomo-o, Herschman Harvey R Transgenic mouse for conditional, tissue-specific Cox-2 overexpression. Genesis (New York, N.Y. : 2000). 2006; 44(4): 177-82.
Chikazu Daichi, Li Xiaodong, Kawaguchi Hiroshi, Sakuma Yoko, Voznesensky Olga S, Adams Douglas J, Xu Manshan, Hoshi Kazuto, Katavic Vedran, Herschman Harvey R, Raisz Lawrence G, Pilbeam Carol C Bone morphogenetic protein 2 induces cyclo-oxygenase 2 in osteoblasts via a Cbfa1 binding site: role in effects of bone morphogenetic protein 2 in vitro and in vivo. 2002. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2005; 20(10): 1888-98.
Yaghoubi Shahriar S, Barrio Jorge R, Namavari Mohammad, Satyamurthy Nagichettiar, Phelps Michael E, Herschman Harvey R, Gambhir Sanjiv S Imaging progress of herpes simplex virus type 1 thymidine kinase suicide gene therapy in living subjects with positron emission tomography. Cancer gene therapy. 2005; 12(3): 329-39.
Toyokuni Tatsushi, Kumar J S Dileep, Walsh Joseph C, Shapiro Alan, Talley John J, Phelps Michael E, Herschman Harvey R, Barrio Jorge R, Satyamurthy Nagichettiar Synthesis of 4-(5-[18F]fluoromethyl-3-phenylisoxazol-4-yl)benzenesulfonamide, a new [18F]fluorinated analogue of valdecoxib, as a potential radiotracer for imaging cyclooxygenase-2 with positron emission tomography. Bioorganic & medicinal chemistry letters. 2005; 15(21): 4699-702.
Ferguson Gregory D, Wang Hongbing, Herschman Harvey R, Storm Daniel R Altered hippocampal short-term plasticity and associative memory in synaptotagmin IV (-/-) mice. Hippocampus. 2004; 14(8): 964-74.
Singh Vinita, Miranda Tina Branscombe, Jiang Wei, Frankel Adam, Roemer Martha E, Robb Victoria A, Gutmann David H, Herschman Harvey R, Clarke Steven, Newsham Irene F DAL-1/4.1B tumor suppressor interacts with protein arginine N-methyltransferase 3 (PRMT3) and inhibits its ability to methylate substrates in vitro and in vivo. Oncogene. 2004; 23(47): 7761-71.
Vician Linda J, Xu Guoping, Liu Wei, Feldman Jonathan D, Machado Hidevaldo B, Herschman Harvey R MAPKAP kinase-2 is a primary response gene induced by depolarization in PC12 cells and in brain. Journal of neuroscience research. 2004; 78(3): 315-28.
Chen Ian Y, Wu Joseph C, Min Jung-Jun, Sundaresan Gobalakrishnan, Lewis Xiaoman, Liang Qianwa, Herschman Harvey R, Gambhir Sanjiv S Micro-positron emission tomography imaging of cardiac gene expression in rats using bicistronic adenoviral vector-mediated gene delivery. Circulation. 2004; 109(11): 1415-20.
Herschman Harvey R Molecular imaging: a view from the inside. Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology. 2004; 11(2): 210-4.
Herschman Harvey R Noninvasive imaging of reporter gene expression in living subjects. Advances in cancer research. 2004; 92(2): 29-80.
Liang Qianwa, Yamamoto Masato, Curiel David T, Herschman Harvey R Noninvasive imaging of transcriptionally restricted transgene expression following intratumoral injection of an adenovirus in which the COX-2 promoter drives a reporter gene. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging. 2004; 6(6): 395-404.
Liang Qianwa, Dmitriev Igor, Kashentseva Elena, Curiel David T, Herschman Harvey R Noninvasive of adenovirus tumor retargeting in living subjects by a soluble adenovirus receptor-epidermal growth factor (sCAR-EGF) fusion protein. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging. 2004; 6(6): 385-94.
Herschman Harvey R PET reporter genes for noninvasive imaging of gene therapy, cell tracking and transgenic analysis. Critical reviews in oncology/hematology. 2004; 51(3): 191-204.
Ferguson Gregory D, Herschman Harvey R, Storm Daniel R Reduced anxiety and depression-like behavior in synaptotagmin IV (-/-) mice. Neuropharmacology. 2004; 47(4): 604-11.
Machado Hidevaldo B, Liu Wei, Vician Linda J, Herschman Harvey R Synaptotagmin IV overexpression inhibits depolarization-induced exocytosis in PC12 cells. Journal of neuroscience research. 2004; 76(3): 334-41.
Smith Jeffrey B, Herschman Harvey R Targeted identification of glucocorticoid-attenuated response genes: in vitro and in vivo models. Proceedings of the American Thoracic Society. 2004; 1(3): 275-81.
Symensma Tonia L, Martinez-Guzman DeeAnn, Jia Qingmei, Bortz Eric, Wu Ting-Ting, Rudra-Ganguly Nandini, Cole Steve, Herschman Harvey, Sun Ren COX-2 induction during murine gammaherpesvirus 68 infection leads to enhancement of viral gene expression. Journal of virology. 2003; 77(23): 12753-63.
Herschman Harvey R, Talley John J, DuBois Raymond Cyclooxygenase 2 (COX-2) as a target for therapy and noninvasive imaging. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging. 2003; 5(5): 286-303.
Liu Wei, Feldman Jonathan D, Machado Hidevaldo B, Vician Linda J, Herschman Harvey R Expression of depolarization-induced immediate early gene proteins in PC12 cells. Journal of neuroscience research. 2003; 72(6): 670-8.
Herschman Harvey R Micro-PET imaging and small animal models of disease. Current opinion in immunology. 2003; 15(4): 378-84.
Herschman Harvey R Molecular imaging: looking at problems, seeing solutions. Science (New York, N.Y.). 2003; 302(5645): 605-8.
Nguyen Julie T, Machado Hidevaldo, Herschman Harvey R Repetitive, noninvasive imaging of cyclooxygenase-2 gene expression in living mice. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging. 2003; 5(4): 248-56.
Chikazu Daichi, Li Xiaodong, Kawaguchi Hiroshi, Sakuma Yoko, Voznesensky Olga S, Adams Douglas J, Xu Manshan, Hoshio Kazuto, Katavic Vedran, Herschman Harvey R, Raisz Lawrence G, Pilbeam Carol C Bone morphogenetic protein 2 induces cyclo-oxygenase 2 in osteoblasts via a Cbfal binding site: role in effects of bone morphogenetic protein 2 in vitro and in vivo. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2002; 17(8): 1430-40.
Smith Jeffrey B, Wadleigh David J, Xia Yu-Rong, Mar Rebecca A, Herschman Harvey R, Lusis Aldons J Cloning and genomic localization of the murine LPS-induced CXC chemokine (LIX) gene, Scyb5. Immunogenetics. 2002; 54(8): 599-603.
Rudra-Ganguly Nandini, Reddy Srinivasa T, Korge Paavo, Herschman Harvey R Diesel exhaust particle extracts and associated polycyclic aromatic hydrocarbons inhibit Cox-2-dependent prostaglandin synthesis in murine macrophages and fibroblasts. The Journal of biological chemistry. 2002; 277(42): 39259-65.
Giza Christopher C, Prins Mayumi L, Hovda David A, Herschman Harvey R, Feldman Jonathan D Genes preferentially induced by depolarization after concussive brain injury: effects of age and injury severity. Journal of neurotrauma. 2002; 19(4): 387-402.
Smith Jeffrey B, Nguyen Tam T, Hughes Heather J, Herschman Harvey R, Widney Daniel P, Bui Kim C, Rovai Leonor E Glucocorticoid-attenuated response genes induced in the lung during endotoxemia. American journal of physiology. Lung cellular and molecular physiology. 2002; 283(3): L636-47.
Green Leeta A, Yap Cecelia S, Nguyen Khoi, Barrio Jorge R, Namavari Mohammad, Satyamurthy Nagichettiar, Phelps Michael E, Sandgren Eric P, Herschman Harvey R, Gambhir Sanjiv S Indirect monitoring of endogenous gene expression by positron emission tomography (PET) imaging of reporter gene expression in transgenic mice. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging. 2002; 4(1): 71-81.
Cimato Thomas R, Tang Jie, Xu Ye, Guarnaccia Corrado, Herschman Harvey R, Pongor Sandor, Aletta John M Nerve growth factor-mediated increases in protein methylation occur predominantly at type I arginine methylation sites and involve protein arginine methyltransferase 1. Journal of neuroscience research. 2002; 67(4): 435-42.
Herschman Harvey R Non-invasive imaging of reporter genes. Journal of cellular biochemistry. Supplement. 2002; 39(4): 36-44.
Liang Qianwa, Gotts Jeff, Satyamurthy Nagichettiar, Barrio Jorge, Phelps Michael E, Gambhir Sanjiv S, Herschman Harvey R Noninvasive, repetitive, quantitative measurement of gene expression from a bicistronic message by positron emission tomography, following gene transfer with adenovirus. Molecular therapy : the journal of the American Society of Gene Therapy. 2002; 6(1): 73-82.
Lin Henry J, Lakkides Karen M, Keku Temitope O, Reddy Srinivasa T, Louie Andrew D, Kau Irving H, Zhou Haiyan, Gim Jason S Y, Ma Hoang L, Matthies Carl F, Dai Aihua, Huang Hsiao-Fen, Materi Alicia M, Lin Jesse H, Frankl Harold D, Lee Eric R, Hardy Steven I, Herschman Harvey R, Henderson Brian E, Kolonel Laurence N, Le Marchand Loïc, Garavito R Michael, Sandler Robert S, Haile Robert W, Smith William L Prostaglandin H synthase 2 variant (Val511Ala) in African Americans may reduce the risk for colorectal neoplasia. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2002; 11(11): 1305-15.