FACULTY RESEARCH
Faculty List
Anna M Wu, Ph.D.
Work Email Address:
awu@mednet.ucla.edu
Work Phone Number:
(310) 794-5088
Laboratory Address:
Crump Institute
Los Angeles, CA 90095
Office Address:
CNSI 4335, Crump Institute,570 Westwood Plaza
Los Angeles, CA 90095
Department / Division Affiliations
| Director, Cancer Molecular Imaging |
| Professor, Biomedical Physics IDP, Molecular & Medical Pharmacology |
| Member, ACCESS Program: Dept. of Molecular & Medical Pharmacology, JCCC Genitourinary Oncology Program Area, DOE Funded Faculty, California NanoSystems Institute |
| Faculty, Cellular and Molecular Pathology PhD Program, Crump Institute for Molecular Imaging |
Publications
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Shimazaki, K., Lepin, E.J., Wei, B., Nagy, A., Coulum, P., Mareninov, S., Fu, M., Wu, A.M., Marks, J.D., Braun, J., Gordon, L.K., and Wadehra, M. Diabodies targeting epithelial membrane protein 2 reduce tumorigenicity of human endometrial cancer cell lines.
Clin. Cancer Res..
2008; 14:
7367-7377.
Kenanova, V.E., Barat, B., Olafsen, T., Chatziioannou, A., Herschman, H.R., Braun, J., and Wu, A.M. Recombinant carcinoembryonic antigen as a reporter gene for molecular imaging.
Eur. J. Nucl. Med. Molec. Imaging.
2008; 36:
104-114.
Sirk, S., Olafsen, T., Barat, B., Bauer, K. B., McCabe, K.E., and Wu, A.M. Site-specific thiol-mediated conjugation of fluorescent probes to cysteine-modified diabodies targeting CD20 or HER2.
Bioconjugate Chemistry.
2008; 19:
2527-2534.
Schipper, M.L., Cheng, Z., Lee, S.-W., Bentolila, L.A., Iyer, G., Rao, J., Chen, X., Wu, A.M., Weiss, S., and Gambhir, S.S. MicroPET-based biodistribution of quantum dots in living mice.
J. Nucl. Med..
2007; 48:
1511-1518.
Olafsen Tove, Sirk Shannon J, Betting David J, Kenanova Vania E, Bauer Karl B, Ladno Waldemar, Raubitschek Andrew A, Timmerman John M, Wu Anna M ImmunoPET imaging of B-cell lymphoma using 124I-anti-CD20 scFv dimers
(diabodies)..
Protein engineering, design & selection : PEDS.
2010; 23(4):
243-9.
Gagnon Pete, Cheung Chia-Wei, Lepin Eric J, Wu Anna M, Sherman Mark A, Raubitschek Andrew A, Yazaki Paul J Minibodies and Multimodal Chromatography Methods: A Convergence of
Challenge and Opportunity..
BioProcess international.
2010; 8(2):
26-35.
Olafsen Tove, Young Stephen G, Davies Brandon S J, Beigneux Anne P, Kenanova Vania E, Voss Constance, Young Glen, Wong Koon-Pong, Barnes Richard H, Tu Yiping, Weinstein Michael M, Nobumori Chika, Huang Sung-Cheng, Goldberg Ira J, Bensadoun André, Wu Anna M, Fong Loren G Unexpected expression pattern for
glycosylphosphatidylinositol-anchored HDL-binding protein 1 (GPIHBP1)
in mouse tissues revealed by positron emission tomography scanning..
The Journal of biological chemistry.
2010; 285(50):
39239-48.
Olafsen Tove, Sirk Shannon J, Olma Sebastian, Shen Clifton K-F, Wu Anna M ImmunoPET using engineered antibody fragments: fluorine-18 labeled
diabodies for same-day imaging..
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine.
2012; 132(2):
.
McCabe Katelyn E, Liu Bin, Marks James D, Tomlinson James S, Wu Hong, Wu Anna M An Engineered Cysteine-Modified Diabody for Imaging Activated
Leukocyte Cell Adhesion Molecule (ALCAM)-Positive Tumors..
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging.
2011; 10(3):
.
Barat Bhaswati, Kenanova Vania E, Olafsen Tove, Wu Anna M Evaluation of two internalizing carcinoembryonic antigen reporter
genes for molecular imaging..
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging.
2011; 13(3):
526-35.
Kenanova Vania E, Olafsen Tove, Salazar Felix B, Williams Lawrence E, Knowles Scott, Wu Anna M Tuning the serum persistence of human serum albumin domain III:diabody
fusion proteins..
Protein engineering, design & selection : PEDS.
2010; 23(10):
789-98.
Frank Richard T, Edmiston Marissa, Kendall Stephen E, Najbauer Joseph, Cheung Chia-Wei, Kassa Thewodros, Metz Marianne Z, Kim Seung U, Glackin Carlotta A, Wu Anna M, Yazaki Paul J, Aboody Karen S Neural stem cells as a novel platform for tumor-specific delivery of
therapeutic antibodies..
PloS one.
2009; 4(12):
e8314.
Wong Jeffrey Y C, Raubitschek Andrew, Yamauchi Dave, Williams Lawrence E, Wu Anna M, Yazaki Paul, Shively John E, Colcher David, Somlo George A pretherapy biodistribution and dosimetry study of
indium-111-radiolabeled trastuzumab in patients with human epidermal
growth factor receptor 2-overexpressing breast cancer..
Cancer biotherapy & radiopharmaceuticals.
2010; 25(4):
387-94.
Afshar Sepideh, Olafsen Tove, Wu Anna M, Morrison Sherie L Characterization of an engineered human purine nucleoside
phosphorylase fused to an anti-her2/neu single chain Fv for use in
ADEPT..
Journal of experimental & clinical cancer research : CR.
2009; 28(12):
147.
Lepin Eric J, Leyton Jeffrey V, Zhou Yu, Olafsen Tove, Salazar Felix B, McCabe Katelyn E, Hahm Scott, Marks James D, Reiter Robert E, Wu Anna M An affinity matured minibody for PET imaging of prostate stem cell
antigen (PSCA)-expressing tumors..
European journal of nuclear medicine and molecular imaging.
2010; 37(8):
1529-38.
Morizono Kouki, Xie Yiming, Olafsen Tove, Lee Benhur, Dasgupta Asim, Wu Anna M, Chen Irvin S Y The soluble serum protein Gas6 bridges virion envelope
phosphatidylserine to the TAM receptor tyrosine kinase Axl to mediate
viral entry..
Cell host & microbe.
2011; 9(4):
286-98.
Sherman David J, Kenanova Vania E, Lepin Eric J, McCabe Katelyn E, Kamei Ken-Ichiro, Ohashi Minori, Wang Shutao, Tseng Hsian-Rong, Wu Anna M, Behrenbruch Christian P A differential cell capture assay for evaluating antibody interactions
with cell surface targets..
Analytical biochemistry.
2010; 401(2):
173-81.
Olafsen Tove, Betting David, Kenanova Vania E, Salazar Felix B, Clarke Pat, Said Jonathan, Raubitschek Andrew A, Timmerman John M, Wu Anna M Recombinant anti-CD20 antibody fragments for small-animal PET imaging
of B-cell lymphomas..
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2009; 50(9):
1500-8.
McCabe Katelyn E, Wu Anna M Positive progress in immunoPET--not just a coincidence..
Cancer biotherapy & radiopharmaceuticals.
2010; 25(3):
253-61.
Barat Bhaswati, Sirk Shannon J, McCabe Katelyn E, Li Jianqing, Lepin Eric J, Remenyi Roland, Koh Ai Leen, Olafsen Tove, Gambhir Sanjiv S, Weiss Shimon, Wu Anna M Cys-diabody quantum dot conjugates (immunoQdots) for cancer marker
detection..
Bioconjugate chemistry.
2009; 20(8):
1474-81.
Vaidyanathan Ganesan, Jestin Emmanuelle, Olafsen Tove, Wu Anna M, Zalutsky Michael R Evaluation of an anti-p185(HER2) (scFv-C(H)2-C(H)3)2 fragment
following radioiodination using two different residualizing labels:
SGMIB and IB-Mal-D-GEEEK..
Nuclear medicine and biology.
2009; 36(6):
671-80.
Olafsen Tove, Wu Anna M Antibody vectors for imaging..
Seminars in nuclear medicine.
2010; 40(3):
167-81.
Liu Kan, Lepin Eric J, Wang Ming-Wei, Guo Feng, Lin Wei-Yu, Chen Yi-Chun, Sirk Shannon J, Olma Sebastian, Phelps Michael E, Zhao Xing-Zhong, Tseng Hsian-Rong, Michael van Dam R, Wu Anna M, Shen Clifton K-F Microfluidic-based 18F-labeling of biomolecules for immuno-positron
emission tomography..
Molecular imaging.
2011; 10(3):
168-76, 1-7.
Liu Kan, Wang Ming-Wei, Lin Wei-Yu, Phung Duy Linh, Girgis Mark D, Wu Anna M, Tomlinson James S, Shen Clifton K-F Molecular Imaging Probe Development using Microfluidics..
Current organic synthesis.
2011; 8(4):
473-487.
Fu Maoyong, Brewer Sarah, Olafsen Tove, Wu Anna M, Gordon Lynn K, Said Jonathan, Braun Jonathan, Wadehra Madhuri Positron Emission Tomography Imaging of Endometrial Cancer Using
Engineered Anti-EMP2 Antibody Fragments..
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging.
2012; 36(3):
.
Knowles Scott M, Wu Anna M Advances in immuno-positron emission tomography: antibodies for
molecular imaging in oncology..
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2012; 30(31):
3884-92.
Girgis Mark D, Kenanova Vania, Olafsen Tove, McCabe Katelyn E, Wu Anna M, Tomlinson James S Anti-CA19-9 diabody as a PET imaging probe for pancreas cancer..
The Journal of surgical research.
2011; 170(2):
169-78.
Andersen Jan Terje, Foss Stian, Kenanova Vania E, Olafsen Tove, Leikfoss Ingvild S, Roopenian Derry C, Wu Anna M, Sandlie Inger Anti-carcinoembryonic antigen single-chain variable fragment antibody
variants bind mouse and human neonatal Fc receptor with different
affinities that reveal distinct cross-species differences in serum
half-life..
The Journal of biological chemistry.
2012; 287(27):
22927-37.
Federman Noah, Chan Jason, Nagy Jon O, Landaw Elliot M, McCabe Katelyn, Wu Anna M, Triche Timothy, Kang Hyunggyoo, Liu Bin, Marks James D, Denny Christopher T Enhanced growth inhibition of osteosarcoma by cytotoxic polymerized
liposomal nanoparticles targeting the alcam cell surface receptor..
Sarcoma.
2012; 2012(2):
126906.
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