FACULTY RESEARCH

Faculty List

Timothy Donahue, M.D.

Work Email Address: tdonahue@mednet.ucla.edu

Fax Number: (310) 206-2472

Office Phone Number: (310) 206-7440

Work Phone Number: (310) 794-7788
(310) 825-9427

http://people.healthsciences.ucla.edu/community/institution/personnel?personnel_id=1879550

Health System

Mailing Address:
UCLA Surg-Surg Onc
BOX 956904
72-215
Los Angeles, CA 90095

Office Address:
10833 Le Conte Ave.
72-256 CHS
Los Angeles, CA 90095

Department / Division Affiliations
Professor, Surgery, General Surgery, Molecular & Medical Pharmacology
Member, CTSI, Immunity, Microbes & Molecular Pathogenesis GPB Home Area, JCCC Cancer and Stem Cell Biology Program Area, Molecular Pharmacology GPB Home Area, themes


Publications

A selected list of publications:

Hill Reginald, Li Yunfeng, Tran Linh M, Dry Sarah, Calvopina Joseph Hargan, Garcia Alejandro, Kim Christine, Wang Ying, Donahue Timothy R, Herschman Harvey R, Wu Hong   Cell intrinsic role of COX-2 in pancreatic cancer development Molecular cancer therapeutics, 2012; 11(10): 2127-37.
Donahue Timothy R, Tran Linh M, Hill Reginald, Li Yunfeng, Kovochich Anne, Hargan Calvopina Joseph, Patel Sanjeet G, Wu Nanping, Hindoyan Antreas, Farrell James J, Li Xinmin, Dawson David W, Wu Hong   Integrative Survival-Based Molecular Profiling of Human Pancreatic Cancer Clinical cancer research : an official journal of the American Association for Cancer Research, 2012; .
Donahue Timothy R, Dawson David W   Nodal/Activin signaling: a novel target for pancreatic cancer stem cell therapy Cell stem cell, 2011; 9(5): 383-4.
Sherman Mara H, Yu Ruth T, Engle Dannielle D, Ding Ning, Atkins Annette R, Tiriac Herve, Collisson Eric A, Connor Frances, Van Dyke Terry, Kozlov Serguei, Martin Philip, Tseng Tiffany W, Dawson David W, Donahue Timothy R, Masamune Atsushi, Shimosegawa Tooru, Apte Minoti V, Wilson Jeremy S, Ng Beverly, Lau Sue Lynn, Gunton Jenny E, Wahl Geoffrey M, Hunter Tony, Drebin Jeffrey A, O'Dwyer Peter J, Liddle Christopher, Tuveson David A, Downes Michael, Evans Ronald M   Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy Cell, 2014; 159(1): 80-93.
Kim Woosuk, Le Thuc M, Wei Liu, Poddar Soumya, Bazzy Jimmy, Wang Xuemeng, Uong Nhu T, Abt Evan R, Capri Joseph R, Austin Wayne R, Van Valkenburgh Juno S, Steele Dalton, Gipson Raymond M, Slavik Roger, Cabebe Anthony E, Taechariyakul Thotsophon, Yaghoubi Shahriar S, Lee Jason T, Sadeghi Saman, Lavie Arnon, Faull Kym F, Witte Owen N, Donahue Timothy R, Phelps Michael E, Herschman Harvey R, Herrmann Ken, Czernin Johannes, Radu Caius G   [18F]CFA as a clinically translatable probe for PET imaging of deoxycytidine kinase activity Proceedings of the National Academy of Sciences of the United States of America, 2016; 113(15): 4027-32.
Le Thuc M, Poddar Soumya, Capri Joseph R, Abt Evan R, Kim Woosuk, Wei Liu, Uong Nhu T, Cheng Chloe M, Braas Daniel, Nikanjam Mina, Rix Peter, Merkurjev Daria, Zaretsky Jesse, Kornblum Harley I, Ribas Antoni, Herschman Harvey R, Whitelegge Julian, Faull Kym F, Donahue Timothy R, Czernin Johannes, Radu Caius G   ATR inhibition facilitates targeting of leukemia dependence on convergent nucleotide biosynthetic pathways Nature communications, 2017; 8(1): 241.
Liu Xiangsheng, Situ Allen, Kang Yanan, Villabroza Katie Rose, Liao Yupei, Chang Chong Hyun, Donahue Timothy, Nel Andre E, Meng Huan   Irinotecan Delivery by Lipid-Coated Mesoporous Silica Nanoparticles Shows Improved Efficacy and Safety over Liposomes for Pancreatic Cancer ACS nano, 2016; 10(2): 2702-15.
Liu Xiangsheng, Lin Paulina, Perrett Ian, Lin Joshua, Liao Yu-Pei, Chang Chong Hyun, Jiang Jinhong, Wu Nanping, Donahue Timothy, Wainberg Zev, Nel Andre E, Meng Huan   Tumor-penetrating peptide enhances transcytosis of silicasome-based chemotherapy for pancreatic cancer The Journal of clinical investigation, 2017; 127(5): 2007-2018.
Elliott Irmina A, Dann Amanda M, Ghukasyan Razmik, Damato Lauren, Girgis Mark D, King Jonathan C, Hines O J, Reber Howard A, Donahue Timothy R   Pasireotide does not prevent postoperative pancreatic fistula: a prospective study HPB : the official journal of the International Hepato Pancreato Biliary Association, 2018; 20(5): 418-422.
Toste Paul A, Nguyen Andrew H, Kadera Brian E, Duong Mindy, Wu Nanping, Gawlas Irmina, Tran Linh M, Bikhchandani Mihir, Li Luyi, Patel Sanjeet G, Dawson David W, Donahue Timothy R   Chemotherapy-Induced Inflammatory Gene Signature and Protumorigenic Phenotype in Pancreatic CAFs via Stress-Associated MAPK Molecular cancer research : MCR, 2016; 14(5): 437-47.
Nguyen Andrew H, Elliott Irmina A, Wu Nanping, Matsumura Cynthia, Vogelauer Maria, Attar Narsis, Dann Amanda, Ghukasyan Razmik, Toste Paul A, Patel Sanjeet G, Williams Jennifer L, Li Luyi, Dawson David W, Radu Caius, Kurdistani Siavash K, Donahue Timothy R   Histone deacetylase inhibitors provoke a tumor supportive phenotype in pancreatic cancer associated fibroblasts Oncotarget, 2017; 8(12): 19074-19088.