Faculty List

Robert Damoiseaux, Ph.D.

Email Address: rdamoiseaux@mednet.ucla.edu
Email Address: robert@cnsi.ucla.edu

Lab Number: 310-983-3304

Office Phone Number: 310-794-1974


Mailing Address:
Mail Code: 148906
2805 Molecular Sciences Bldg.
Los Angeles, CA 90095

Work Address:
California NanoSystems Institute
570 Westwood Plaza
Bldg 114
Los Angeles, CA 90095

Department / Division Affiliations
Director, Molecular Screening Shared Resource (MSSR)
Professor, Molecular & Medical Pharmacology
Member, Molecular Pharmacology GPB Home Area

Research Interests
Robert Damoiseaux, Ph.D. is a High Throughput Screening (HTS) expert and a professor in the Department of Molecular and Medical Pharmacology of the David Geffen School of Medicine. His research interests focus on the development of novel HTS technologies. He also directs the Molecular Screening Shared Resource (MSSR) which is a cutting edge facility involved in research projects with, among others, UCLA, Caltech, and the biotech and pharmaceutical industries. He received his PhD at the University of Lausanne under Dr. Kai Johnsson (currently director at the Max Planck Institute for Medical Research, Munich) and then joined the Institute for Functional Genomics (GNF, Novartis) where he was in charge of the development of the next generation assay platform for proteases. He authored over 100 manuscripts and patents on high throughput screening and synthesis, was recognized as expert author in Wiley’s Development of Therapeutic Agents Handbook and is also an editor for Springers Current Protocols in Molecular biology. He is also member of the NIH study section and special emphasis panel reviewing high throughput screening grants. His expertise in high-through-put screening and the use of novel technologies brings him into demand for scientific collaborations and consulting for both academia and industry.


A selected list of publications:

Meng H, Mai WX, Zhang H, Xue M, Xia T, Lin S, Wang X, Zhao Y, Ji Z, Zink JI, Nel AE, Damoiseaux, R.   Codelivery of an optimal drug/siRNA combination using mesoporous silica nanoparticles to overcome drug resistance in breast cancer in vitro and in vivo ACS Nano, 2013; 7(2): 994-1005.
Li Ming, van Zee Mark, Riche Carson T, Tofig Bobby, Gallaher Sean D, Merchant Sabeeha S, Damoiseaux Robert, Goda Keisuke, Di Carlo Dino   A Gelatin Microdroplet Platform for High-Throughput Sorting of Hyperproducing Single-Cell-Derived Microalgal Clones Small (Weinheim an der Bergstrasse, Germany), 2018; e1803315.
Tekin Elif, White Cynthia, Kang Tina Manzhu, Singh Nina, Cruz-Loya Mauricio, Damoiseaux Robert, Savage Van M, Yeh Pamela J   Prevalence and patterns of higher-order drug interactions in NPJ systems biology and applications, 2018; 4: 31.
Xu Shili, Catapang Arthur, Braas Daniel, Stiles Linsey, Doh Hanna M, Lee Jason T, Graeber Thomas G, Damoiseaux Robert, Shirihai Orian, Herschman Harvey R   A precision therapeutic strategy for hexokinase 1-null, hexokinase 2-positive cancers Cancer & metabolism, 2018; 6: 7.
Orfanos Sarah, Jude Joseph, Deeney Brian Thomas, Cao Gaoyuan, Rastogi Deepa, van Zee Mark, Pushkarsky Ivan, Munoz Hector E, Damoiseaux Robert, Di Carlo Dino, Panettieri Reynold   Obesity increases airway smooth muscle responses to contractile agonists American journal of physiology. Lung cellular and molecular physiology, 2018; 4: 31.
Cruz-Loya Mauricio, Kang Tina Manzhu, Lozano Natalie Ann, Watanabe Rina, Tekin Elif, Damoiseaux Robert, Savage Van M, Yeh Pamela J   Stressor interaction networks suggest antibiotic resistance co-opted from stress responses to temperature The ISME journal, 2018; 4: 31.
Laks Dan R, Oses-Prieto Juan A, Alvarado Alvaro G, Nakashima Jonathan, Chand Shreya, Azzam Daniel B, Gholkar Ankur A, Sperry Jantzen, Ludwig Kirsten, Condro Michael C, Nazarian Serli, Cardenas Anjelica, Shih Michelle Y S, Damoiseaux Robert, France Bryan, Orozco Nicholas, Visnyei Koppany, Crisman Thomas J, Gao Fuying, Torres Jorge Z, Coppola Giovanni, Burlingame Alma L, Kornblum Harley I   A molecular cascade modulates MAP1B and confers resistance to mTOR inhibition in human glioblastoma Neuro-oncology, 2018; 20(6): 764-775.
Hong Aayoung, Moriceau Gatien, Sun Lu, Lomeli Shirley, Piva Marco, Damoiseaux Robert, Holmen Sheri L, Sharpless Norman E, Hugo Willy, Lo Roger S   Exploiting Drug Addiction Mechanisms to Select against MAPKi-Resistant Melanoma Cancer discovery, 2018; 8(1): 74-93.
Keegan Alissa, Plath Kathrin, Damoiseaux Robert   High-Throughput Screening of a Luciferase Reporter of Gene Silencing on the Inactive X Chromosome Methods in molecular biology (Clifton, N.J.), 2018; 1755(1): 75-87.
Welch Genevieve, Damoiseaux Robert, Miraglia Loren   Making It All Work: Functional Genomics and Reporter Gene Assays Methods in molecular biology (Clifton, N.J.), 2018; 1755(1): 89-105.
Welch Genevieve, Damoiseaux Robert, Miraglia Loren   Reporter Gene Assays Using Transfectable Functional Genomics Libraries Methods in molecular biology (Clifton, N.J.), 2018; 1755(1): 107-120.
Welch Genevieve, Damoiseaux Robert, Miraglia Loren   Reporter Gene Assays Using Viral Functional Genomics Libraries Methods in molecular biology (Clifton, N.J.), 2018; 1755(1): 121-133.
Bowers Peter M, Boyle William J, Damoiseaux Robert   The Use of Somatic Hypermutation for the Affinity Maturation of Therapeutic Antibodies Methods in molecular biology (Clifton, N.J.), 2018; 1827(1): 479-489.
Yoo Edwin J, Cao Gaoyuan, Koziol-White Cynthia J, Ojiaku Christie A, Sunder Krishna, Jude Joseph A, Michael James V, Lam Hong, Pushkarsky Ivan, Damoiseaux Robert, Di Carlo Dino, Ahn Kwangmi, An Steven S, Penn Raymond B, Panettieri Reynold A   British journal of pharmacology, 2017; 174(23): 4383-4395.
Senese Silvia, Lo Yu-Chen, Gholkar Ankur A, Li Chien-Ming, Huang Yong, Mottahedeh Jack, Kornblum Harley I, Damoiseaux Robert, Torres Jorge Z   Microtubins: a novel class of small synthetic microtubule targeting drugs that inhibit cancer cell proliferation Oncotarget, 2017; 8(61): 104007-104021.
Song Chunying, Piva Marco, Sun Lu, Hong Aayoung, Moriceau Gatien, Kong Xiangju, Zhang Hong, Lomeli Shirley, Qian Jin, Yu Clarissa C, Damoiseaux Robert, Kelley Mark C, Dahlman Kimberley B, Scumpia Philip O, Sosman Jeffrey A, Johnson Douglas B, Ribas Antoni, Hugo Willy, Lo Roger S   Recurrent Tumor Cell-Intrinsic and -Extrinsic Alterations during MAPKi-Induced Melanoma Regression and Early Adaptation Cancer discovery, 2017; 7(11): 1248-1265.
Watanabe Momoko, Buth Jessie E, Vishlaghi Neda, de la Torre-Ubieta Luis, Taxidis Jiannis, Khakh Baljit S, Coppola Giovanni, Pearson Caroline A, Yamauchi Ken, Gong Danyang, Dai Xinghong, Damoiseaux Robert, Aliyari Roghiyh, Liebscher Simone, Schenke-Layland Katja, Caneda Christine, Huang Eric J, Zhang Ye, Cheng Genhong, Geschwind Daniel H, Golshani Peyman, Sun Ren, Novitch Bennett G   Self-Organized Cerebral Organoids with Human-Specific Features Predict Effective Drugs to Combat Zika Virus Infection Cell reports, 2017; 21(2): 517-532.
Lo Yu-Chen, Senese Silvia, France Bryan, Gholkar Ankur A, Damoiseaux Robert, Torres Jorge Z   Computational Cell Cycle Profiling of Cancer Cells for Prioritizing FDA-Approved Drugs with Repurposing Potential Scientific reports, 2017; 7(1): 11261.
Micewicz Ewa D, Kim Kwanghee, Iwamoto Keisuke S, Ratikan Josephine A, Cheng Genhong, Boxx Gayle M, Damoiseaux Robert D, Whitelegge Julian P, Ruchala Piotr, Nguyen Christine, Purbey Prabhat, Loo Joseph, Deng Gang, Jung Michael E, Sayre James W, Norris Andrew J, Schaue Dörthe, McBride William H   4-(Nitrophenylsulfonyl)piperazines mitigate radiation damage to multiple tissues PloS one, 2017; 12(7): e0181577.
Olugbami Jeremiah Olorunjuwon, Damoiseaux Robert, France Bryan, Onibiyo Esther Modupe, Gbadegesin Michael Adedapo, Sharma Shivani, Gimzewski James Kazimierz, Odunola Oyeronke Adunni   A comparative assessment of antiproliferative properties of resveratrol and ethanol leaf extract of Anogeissus leiocarpus (DC) Guill and Perr against HepG2 hepatocarcinoma cells BMC complementary and alternative medicine, 2017; 17(1): 381.
Hershman Jerome M, France Bryan, Hon Kevin, Damoiseaux Robert   Direct quantification of gamma H2AX by cell-based high throughput screening for evaluation of genotoxicity of pesticides in a human thyroid cell lines Environmental and molecular mutagenesis, 2017; 58(7): 522-528.
Olugbami Jeremiah Olorunjuwon, Damoiseaux Robert, France Bryan, Gbadegesin Michael A, Stieg Adam Z, Sharma Shivani, Odunola Oyeronke A, Gimzewski James K   Atomic force microscopy correlates antimetastatic potentials of HepG2 cell line with its redox/energy status: effects of curcumin and Khaya senegalensis Journal of integrative medicine, 2017; 15(3): 214-230.
Garcia-Diaz Angel, Shin Daniel Sanghoon, Moreno Blanca Homet, Saco Justin, Escuin-Ordinas Helena, Rodriguez Gabriel Abril, Zaretsky Jesse M, Sun Lu, Hugo Willy, Wang Xiaoyan, Parisi Giulia, Saus Cristina Puig, Torrejon Davis Y, Graeber Thomas G, Comin-Anduix Begonya, Hu-Lieskovan Siwen, Damoiseaux Robert, Lo Roger S, Ribas Antoni   Interferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression Cell reports, 2017; 19(6): 1189-1201.
Beppler Casey, Tekin Elif, White Cynthia, Mao Zhiyuan, Miller Jeffrey H, Damoiseaux Robert, Savage Van M, Yeh Pamela J   When more is less: Emergent suppressive interactions in three-drug combinations BMC microbiology, 2017; 17(1): 107.
Soh Lemuel M J, Mak Wai Shun, Lin Paul P, Mi Luo, Chen Frederic Y-H, Damoiseaux Robert, Siegel Justin B, Liao James C   Engineering a Thermostable Keto Acid Decarboxylase Using Directed Evolution and Computationally Directed Protein Design ACS synthetic biology, 2017; 6(4): 610-618.
Miyata Non, Tang Zhiye, Conti Michael A, Johnson Meghan E, Douglas Colin J, Hasson Samuel A, Damoiseaux Robert, Chang Chia-En A, Koehler Carla M   Adaptation of a Genetic Screen Reveals an Inhibitor for Mitochondrial Protein Import Component Tim44 The Journal of biological chemistry, 2017; 292(13): 5429-5442.
Koziol-White Cynthia J, Yoo Edwin J, Cao Gaoyuan, Zhang Jie, Papanikolaou Eleni, Pushkarsky Ivan, Andrews Adam, Himes Blanca E, Damoiseaux Robert D, Liggett Stephen B, Di Carlo Dino, Kurten Richard C, Panettieri Reynold A   Inhibition of PI3K promotes dilation of human small airways in a rho kinase-dependent manner British journal of pharmacology, 2016; 173(18): 2726-38.
Lo Yu-Chen, Senese Silvia, Damoiseaux Robert, Torres Jorge Z   3D Chemical Similarity Networks for Structure-Based Target Prediction and Scaffold Hopping ACS chemical biology, 2016; 11(8): 2244-53.
Wu Tung-Yun, Chen Chang-Ting, Liu Jessica Tse-Jin, Bogorad Igor W, Damoiseaux Robert, Liao James C   Characterization and evolution of an activator-independent methanol dehydrogenase from Cupriavidus necator N-1 Applied microbiology and biotechnology, 2016; 100(11): 4969-83.
Reyes Vincent C, Spitzmiller Melissa R, Hong-Hermesdorf Anne, Kropat Janette, Damoiseaux Robert D, Merchant Sabeeha S, Mahendra Shaily   Copper status of exposed microorganisms influences susceptibility to metallic nanoparticles Environmental toxicology and chemistry, 2016; 35(5): 1148-58.
Minkovsky Alissa, Sahakyan Anna, Bonora Giancarlo, Damoiseaux Robert, Dimitrova Elizabeth, Rubbi Liudmilla, Pellegrini Matteo, Radu Caius G, Plath Kathrin   A high-throughput screen of inactive X chromosome reactivation identifies the enhancement of DNA demethylation by 5-aza-2'-dC upon inhibition of ribonucleotide reductase Epigenetics & chromatin, 2015; 8(3): 42.
Zuo Jun, Kye Steve, Quinn Kevin K, Cooper Paige, Damoiseaux Robert, Krogstad Paul   Discovery of Structurally Diverse Small-Molecule Compounds with Broad Antiviral Activity against Enteroviruses Antimicrobial agents and chemotherapy, 2015; 60(3): 1615-26.
Huynh Thu P, Barwe Sonali P, Lee Seung J, McSpadden Ryan, Franco Omar E, Hayward Simon W, Damoiseaux Robert, Grubbs Stephen S, Petrelli Nicholas J, Rajasekaran Ayyappan K   Glucocorticoids suppress renal cell carcinoma progression by enhancing Na,K-ATPase beta-1 subunit expression PloS one, 2015; 10(4): e0122442.
Rathbun Jessica Y, Droniou Magali E, Damoiseaux Robert, Haworth Kevin G, Henley Jill E, Exline Colin M, Choe Hyeryun, Cannon Paula M   Novel Arenavirus Entry Inhibitors Discovered by Using a Minigenome Rescue System for High-Throughput Drug Screening Journal of virology, 2015; 89(16): 8428-43.
Ting Pamela Y, Damoiseaux Robert, Titz Björn, Bradley Kenneth A, Graeber Thomas G, Fernández-Vega Virneliz, Bannister Thomas D, Chase Peter, Nair Reji, Scampavia Louis, Hodder Peter, Spicer Timothy P, Colicelli John   Identification of small molecules that disrupt signaling between ABL and its positive regulator RIN1 PloS one, 2015; 10(3): e0121833.
Lo Yu-Chen, Senese Silvia, Li Chien-Ming, Hu Qiyang, Huang Yong, Damoiseaux Robert, Torres Jorge Z   Large-scale chemical similarity networks for target profiling of compounds identified in cell-based chemical screens PLoS computational biology, 2015; 11(3): e1004153.
Parodi Daniela A, Damoiseaux Robert, Allard Patrick   Comprehensive assessment of germline chemical toxicity using the nematode Caenorhabditis elegans Journal of visualized experiments : JoVE, 2015; 10(96): e0121833.
Eshraghi Aria, Dixon Shandee D, Tamilselvam Batcha, Kim Emily Jin-Kyung, Gargi Amandeep, Kulik Julia C, Damoiseaux Robert, Blanke Steven R, Bradley Kenneth A   Cytolethal distending toxins require components of the ER-associated degradation pathway for host cell entry PLoS pathogens, 2014; 10(7): e1004295.
Damoiseaux Robert   UCLA's Molecular Screening Shared Resource: enhancing small molecule discovery with functional genomics and new technology Combinatorial chemistry & high throughput screening, 2014; 17(4): 356-68.
Kim Kyun-Do, Srikanth Sonal, Tan Yossan-Var, Yee Ma-Khin, Jew Marcus, Damoiseaux Robert, Jung Michael E, Shimizu Saki, An Dong Sung, Ribalet Bernard, Waschek James A, Gwack Yousang   Calcium signaling via Orai1 is essential for induction of the nuclear orphan receptor pathway to drive Th17 differentiation Journal of immunology (Baltimore, Md. : 1950), 2014; 192(1): 110-22.
Gillespie Eugene J, Ho Chi-Lee C, Balaji Kavitha, Clemens Daniel L, Deng Gang, Wang Yao E, Elsaesser Heidi J, Tamilselvam Batcha, Gargi Amandeep, Dixon Shandee D, France Bryan, Chamberlain Brian T, Blanke Steven R, Cheng Genhong, de la Torre Juan Carlos, Brooks David G, Jung Michael E, Colicelli John, Damoiseaux Robert, Bradley Kenneth A   Selective inhibitor of endosomal trafficking pathways exploited by multiple toxins and viruses Proceedings of the National Academy of Sciences of the United States of America, 2013; 110(50): E4904-12.
Solaimani Parrisa, Damoiseaux Robert, Hankinson Oliver   Genome-wide RNAi high-throughput screen identifies proteins necessary for the AHR-dependent induction of CYP1A1 by 2,3,7,8-tetrachlorodibenzo-p-dioxin Toxicological sciences : an official journal of the Society of Toxicology, 2013; 136(1): 107-19.
Du Liutao, Jung Michael E, Damoiseaux Robert, Completo Gladys, Fike Francesca, Ku Jin-Mo, Nahas Shareef, Piao Cijing, Hu Hailiang, Gatti Richard A   A new series of small molecular weight compounds induce read through of all three types of nonsense mutations in the ATM gene Molecular therapy : the journal of the American Society of Gene Therapy, 2013; 21(9): 1653-60.
Murphy Jennifer M, Armijo Amanda L, Nomme Julian, Lee Chi Hang, Smith Quentin A, Li Zheng, Campbell Dean O, Liao Hsiang-I, Nathanson David A, Austin Wayne R, Lee Jason T, Darvish Ryan, Wei Liu, Wang Jue, Su Ying, Damoiseaux Robert, Sadeghi Saman, Phelps Michael E, Herschman Harvey R, Czernin Johannes, Alexandrova Anastassia N, Jung Michael E, Lavie Arnon, Radu Caius G   Development of new deoxycytidine kinase inhibitors and noninvasive in vivo evaluation using positron emission tomography Journal of medicinal chemistry, 2013; 56(17): 6696-708.
Zheng Sika, Damoiseaux Robert, Chen Liang, Black Douglas L   A broadly applicable high-throughput screening strategy identifies new regulators of Dlg4 (Psd-95) alternative splicing Genome research, 2013; 23(6): 998-1007.
Xiong Sijing, George Saji, Yu Haiyang, Damoiseaux Robert, France Bryan, Ng Kee Woei, Loo Joachim Say-Chye   Size influences the cytotoxicity of poly (lactic-co-glycolic acid) (PLGA) and titanium dioxide (TiO(2)) nanoparticles Archives of toxicology, 2013; 87(6): 1075-86.
Lin Sijie, Zhao Yan, Ji Zhaoxia, Ear Jason, Chang Chong Hyun, Zhang Haiyuan, Low-Kam Cecile, Yamada Kristin, Meng Huan, Wang Xiang, Liu Rong, Pokhrel Suman, Mädler Lutz, Damoiseaux Robert, Xia Tian, Godwin Hilary A, Lin Shuo, Nel André E   Zebrafish high-throughput screening to study the impact of dissolvable metal oxide nanoparticles on the hatching enzyme, ZHE1 Small (Weinheim an der Bergstrasse, Germany), 2013; 9(9-10): 1776-85.
Dabir Deepa V, Hasson Samuel A, Setoguchi Kiyoko, Johnson Meghan E, Wongkongkathep Piriya, Douglas Colin J, Zimmerman Johannes, Damoiseaux Robert, Teitell Michael A, Koehler Carla M   A small molecule inhibitor of redox-regulated protein translocation into mitochondria Developmental cell, 2013; 25(1): 81-92.
Fung Eileen, Sugianto Priscilla, Hsu Jason, Damoiseaux Robert, Ganz Tomas, Nemeth Elizabeta   High-throughput screening of small molecules identifies hepcidin antagonists Molecular pharmacology, 2013; 83(3): 681-90.
Xiong Sijing, George Saji, Ji Zhaoxia, Lin Sijie, Yu Haiyang, Damoiseaux Robert, France Bryan, Ng Kee Woei, Loo Say Chye Joachim   Size of TiO(2) nanoparticles influences their phototoxicity: an in vitro investigation Archives of toxicology, 2013; 87(1): 99-109.
Kendall Genevieve C, Mokhonova Ekaterina I, Moran Miriana, Sejbuk Natalia E, Wang Derek W, Silva Oscar, Wang Richard T, Martinez Leonel, Lu Qi L, Damoiseaux Robert, Spencer Melissa J, Nelson Stanley F, Miceli M Carrie   Dantrolene enhances antisense-mediated exon skipping in human and mouse models of Duchenne muscular dystrophy Science translational medicine, 2012; 4(164): 164ra160.
Reyes Vincent C, Li Minghua, Hoek Eric M V, Mahendra Shaily, Damoiseaux Robert   Genome-wide assessment in Escherichia coli reveals time-dependent nanotoxicity paradigms ACS nano, 2012; 6(11): 9402-15.
Zuo Jun, Quinn Kevin K, Kye Steve, Cooper Paige, Damoiseaux Robert, Krogstad Paul   Fluoxetine is a potent inhibitor of coxsackievirus replication Antimicrobial agents and chemotherapy, 2012; 56(9): 4838-44.
Tsirulnikov Kirill, Abuladze Natalia, Bragin Anatol, Faull Kym, Cascio Duilio, Damoiseaux Robert, Schibler Matthew J, Pushkin Alexander   Inhibition of aminoacylase 3 protects rat brain cortex neuronal cells from the toxicity of 4-hydroxy-2-nonenal mercapturate and 4-hydroxy-2-nonenal Toxicology and applied pharmacology, 2012; 263(3): 303-14.
Tai Sheng, Sun Yin, Liu Nan, Ding Boxiao, Hsia Elaine, Bhuta Sunita, Thor Ryan K, Damoiseaux Robert, Liang Chaozhao, Huang Jiaoti   Combination of Rad001 (everolimus) and propachlor synergistically induces apoptosis through enhanced autophagy in prostate cancer cells Molecular cancer therapeutics, 2012; 11(6): 1320-31.
Fung Andrew O, Damoiseaux Robert, Grundeen Sarah, Panes Jonnas L, Horton Daniel H, Judy Jack W, Moore Theodore B   Quantitative detection of PfHRP2 in saliva of malaria patients in the Philippines Malaria journal, 2012; 11(6): 175.
Zhang Haiyuan, Ji Zhaoxia, Xia Tian, Meng Huan, Low-Kam Cecile, Liu Rong, Pokhrel Suman, Lin Sijie, Wang Xiang, Liao Yu-Pei, Wang Meiying, Li Linjiang, Rallo Robert, Damoiseaux Robert, Telesca Donatello, Mädler Lutz, Cohen Yoram, Zink Jeffrey I, Nel Andre E   Use of Metal Oxide Nanoparticle Band Gap To Develop a Predictive Paradigm for Oxidative Stress and Acute Pulmonary Inflammation ACS nano, 2012; .
Liu Rong, Lin Sijie, Rallo Robert, Zhao Yan, Damoiseaux Robert, Xia Tian, Lin Shuo, Nel Andre, Cohen Yoram   Automated phenotype recognition for zebrafish embryo based in vivo high throughput toxicity screening of engineered nano-materials PloS one, 2012; 7(4): e35014.
Ivask Angela, Suarez Elizabeth, Patel Trina, Boren David, Ji Zhaoxia, Holden Patricia, Telesca Donatello, Damoiseaux Robert, Bradley Kenneth A, Godwin Hilary   Genome-wide bacterial toxicity screening uncovers the mechanisms of toxicity of a cationic polystyrene nanomaterial Environmental science & technology, 2012; 46(4): 2398-405.
Visnyei Koppany, Onodera Hideyuki, Damoiseaux Robert, Saigusa Kuniyasu, Petrosyan Syuzanna, De Vries David, Ferrari Denise, Saxe Jonathan, Panosyan Eduard H, Masterman-Smith Michael, Mottahedeh Jack, Bradley Kenneth A, Huang Jing, Sabatti Chiara, Nakano Ichiro, Kornblum Harley I   A molecular screening approach to identify and characterize inhibitors of glioblastoma stem cells Molecular cancer therapeutics, 2011; 10(10): 1818-28.
Li Minghua, Noriega-Trevino Maria Eugenia, Nino-Martinez Nereyda, Marambio-Jones Catalina, Wang Jinwen, Damoiseaux Robert, Ruiz Facundo, Hoek Eric M V   Synergistic bactericidal activity of Ag-TiO₂ nanoparticles in both light and dark conditions Environmental science & technology, 2011; 45(20): 8989-95.
Lin Sijie, Zhao Yan, Xia Tian, Meng Huan, Ji Zhaoxia, Liu Rong, George Saji, Xiong Sijing, Wang Xiang, Zhang Haiyuan, Pokhrel Suman, Mädler Lutz, Damoiseaux Robert, Lin Shuo, Nel Andre E   High content screening in zebrafish speeds up hazard ranking of transition metal oxide nanoparticles ACS nano, 2011; 5(9): 7284-95.
Miraglia Loren, King Fred, Damoiseaux Robert   Seeing the Light: Luminescent Reporter Gene Assays Combinatorial chemistry & high throughput screening, 2011; .
Zhang Haiyuan, Xia Tian, Meng Huan, Xue Min, George Saji, Ji Zhaoxia, Wang Xiang, Liu Rong, Wang Meiying, France Bryan, Rallo Robert, Damoiseaux Robert, Cohen Yoram, Bradley Kenneth A, Zink Jeffrey I, Nel Andre E   Differential expression of syndecan-1 mediates cationic nanoparticle toxicity in undifferentiated versus differentiated normal human bronchial epithelial cells ACS nano, 2011; 5(4): 2756-69.
Damoiseaux R, George S, Li M, Pokhrel S, Ji Z, France B, Xia T, Suarez E, Rallo R, Mädler L, Cohen Y, Hoek E M V, Nel A   No time to lose--high throughput screening to assess nanomaterial safety Nanoscale, 2011; 3(4): 1345-60.
Kim Kwanghee, Damoiseaux Robert, Norris Andrew J, Rivina Leena, Bradley Kenneth, Jung Michael E, Gatti Richard A, Schiestl Robert H, McBride William H   High throughput screening of small molecule libraries for modifiers of radiation responses International journal of radiation biology, 2011; 5(3): .
George Saji, Xia Tian, Rallo Robert, Zhao Yan, Ji Zhaoxia, Lin Sijie, Wang Xiang, Zhang Haiyuan, France Bryan, Schoenfeld David, Damoiseaux Robert, Liu Rong, Lin Shuo, Bradley Kenneth A, Cohen Yoram, Nel André E   Use of a high-throughput screening approach coupled with in vivo zebrafish embryo screening to develop hazard ranking for engineered nanomaterials ACS nano, 2011; 5(3): 1805-17.
Walter Martin A, Benz Matthias R, Hildebrandt Isabel J, Laing Rachel E, Hartung Verena, Damoiseaux Robert D, Bockisch Andreas, Phelps Michael E, Czernin Johannes, Weber Wolfgang A   Metabolic imaging allows early prediction of response to vandetanib Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2011; 52(2): 231-40.
Kamei Ken-ichiro, Sun Jing, Tseng Hsian-Rong, Damoiseaux Robert   Microfluidic image cytometry Methods in molecular biology (Clifton, N.J.), 2011; 706(2): 191-206.
Rallo Robert, France Bryan, Liu Rong, Nair Sumitra, George Saji, Damoiseaux Robert, Giralt Francesc, Nel Andre, Bradley Kenneth, Cohen Yoram   Self-Organizing Map Analysis of Toxicity-Related Cell Signaling Pathways for Metal and Metal Oxide Nanoparticles Environmental science & technology, 2011; 52(2): .
Li Minghua, Pokhrel Suman, Jin Xue, Mädler Lutz, Damoiseaux Robert, Hoek Eric M V   Stability, bioavailability, and bacterial toxicity of ZnO and iron-doped ZnO nanoparticles in aquatic media Environmental science & technology, 2011; 45(2): 755-61.
Jin Xue, Li Minghua, Wang Jinwen, Marambio-Jones Catalina, Peng Fubing, Huang Xiaofei, Damoiseaux Robert, Hoek Eric M V   High-throughput screening of silver nanoparticle stability and bacterial inactivation in aquatic media: influence of specific ions Environmental science & technology, 2010; 44(19): 7321-8.
Peng Fubing, Hoek Eric M V, Damoiseaux Robert   High-content screening for biofilm assays Journal of biomolecular screening, 2010; 15(7): 748-54.
Aghajan Mariam, Jonai Nao, Flick Karin, Fu Fei, Luo Manlin, Cai Xiaolu, Ouni Ikram, Pierce Nathan, Tang Xiaobo, Lomenick Brett, Damoiseaux Robert, Hao Rui, Del Moral Pierre M, Verma Rati, Li Ying, Li Cheng, Houk Kendall N, Jung Michael E, Zheng Ning, Huang Lan, Deshaies Raymond J, Kaiser Peter, Huang Jing   Chemical genetics screen for enhancers of rapamycin identifies a specific inhibitor of an SCF family E3 ubiquitin ligase Nature biotechnology, 2010; 28(7): 738-42.
Hasson Samuel A, Damoiseaux Robert, Glavin Jenny D, Dabir Deepa V, Walker Scott S, Koehler Carla M   Substrate specificity of the TIM22 mitochondrial import pathway revealed with small molecule inhibitor of protein translocation Proceedings of the National Academy of Sciences of the United States of America, 2010; 107(21): 9578-83.
Wolf Mike C, Freiberg Alexander N, Zhang Tinghu, Akyol-Ataman Zeynep, Grock Andrew, Hong Patrick W, Li Jianrong, Watson Natalya F, Fang Angela Q, Aguilar Hector C, Porotto Matteo, Honko Anna N, Damoiseaux Robert, Miller John P, Woodson Sara E, Chantasirivisal Steven, Fontanes Vanessa, Negrete Oscar A, Krogstad Paul, Dasgupta Asim, Moscona Anne, Hensley Lisa E, Whelan Sean P, Faull Kym F, Holbrook Michael R, Jung Michael E, Lee Benhur   A broad-spectrum antiviral targeting entry of enveloped viruses Proceedings of the National Academy of Sciences of the United States of America, 2010; 107(7): 3157-62.
Lee Delphine J, Li Huiying, Ochoa Maria T, Tanaka Motoyuki, Carbone Ryan J, Damoiseaux Robert, Burdick Anne, Sarno Euzenir N, Rea Thomas H, Modlin Robert L   Integrated pathways for neutrophil recruitment and inflammation in leprosy The Journal of infectious diseases, 2010; 201(4): 558-69.
Ohno Izumi, Eibl Guido, Odinokova Irina, Edderkaoui Mouad, Damoiseaux Robert D, Yazbec Moussa, Abrol Ravinder, Goddard William A, Yokosuka Osamu, Pandol Stephen J, Gukovskaya Anna S   Rottlerin stimulates apoptosis in pancreatic cancer cells through interactions with proteins of the Bcl-2 family American journal of physiology. Gastrointestinal and liver physiology, 2010; 298(1): G63-73.
George Saji, Pokhrel Suman, Xia Tian, Gilbert Benjamin, Ji Zhaoxia, Schowalter Marco, Rosenauer Andreas, Damoiseaux Robert, Bradley Kenneth A, Mädler Lutz, Nel André E   Use of a rapid cytotoxicity screening approach to engineer a safer zinc oxide nanoparticle through iron doping ACS nano, 2010; 4(1): 15-29.
Kim Kwanghee, Pollard Julianne M, Norris Andrew J, McDonald J Tyson, Sun Yingli, Micewicz Ewa, Pettijohn Kelly, Damoiseaux Robert, Iwamoto Keisuke S, Sayre James W, Price Brendan D, Gatti Richard A, McBride William H   High-throughput screening identifies two classes of antibiotics as radioprotectors: tetracyclines and fluoroquinolones Clinical cancer research : an official journal of the American Association for Cancer Research, 2009; 15(23): 7238-45.
Suree Nuttee, Yi Sung Wook, Thieu William, Marohn Melanie, Damoiseaux Robert, Chan Albert, Jung Michael E, Clubb Robert T   Discovery and structure-activity relationship analysis of Staphylococcus aureus sortase A inhibitors Bioorganic & medicinal chemistry, 2009; 17(20): 7174-85.
Du Liutao, Damoiseaux Robert, Nahas Shareef, Gao Kun, Hu Hailiang, Pollard Julianne M, Goldstine Jimena, Jung Michael E, Henning Susanne M, Bertoni Carmen, Gatti Richard A   Nonaminoglycoside compounds induce readthrough of nonsense mutations The Journal of experimental medicine, 2009; 206(10): 2285-97.
Damoiseaux Robert, Sherman Sean P, Alva Jackelyn A, Peterson Cory, Pyle April D   Integrated chemical genomics reveals modifiers of survival in human embryonic stem cells Stem cells (Dayton, Ohio), 2009; 27(3): 533-42.
Poulos Jason L, Jeon Tae-Joon, Damoiseaux Robert, Gillespie Eugene J, Bradley Kenneth A, Schmidt Jacob J   Ion channel and toxin measurement using a high throughput lipid membrane platform Biosensors & bioelectronics, 2009; 24(6): 1806-10.
Stoilov Peter, Lin Chia-Ho, Damoiseaux Robert, Nikolic Julia, Black Douglas L   A high-throughput screening strategy identifies cardiotonic steroids as alternative splicing modulators Proceedings of the National Academy of Sciences of the United States of America, 2008; 105(32): 11218-23.
Lee Shaoying, Deng Hongyu, Yu Fuqu, Melega William P, Damoiseaux Robert, Bradley Kenneth A, Sun Ren   Regulation of Kaposi's sarcoma-associated herpesvirus reactivation by dopamine receptor-mediated signaling pathways Journal of acquired immune deficiency syndromes (1999), 2008; 48(5): 531-40.
Sanchez Ana M, Thomas Diane, Gillespie Eugene J, Damoiseaux Robert, Rogers Joseph, Saxe Jonathan P, Huang Jing, Manchester Marianne, Bradley Kenneth A   Amiodarone and bepridil inhibit anthrax toxin entry into host cells Antimicrobial agents and chemotherapy, 2007; 51(7): 2403-11.
Waki Hironori, Park Kye Won, Mitro Nico, Pei Liming, Damoiseaux Robert, Wilpitz Damien C, Reue Karen, Saez Enrique, Tontonoz Peter   The small molecule harmine is an antidiabetic cell-type-specific regulator of PPARgamma expression Cell metabolism, 2007; 5(5): 357-70.
Wu Xinrong, Zhong Hanbing, Song Jianbo, Damoiseaux Robert, Yang Zhen, Lin Shuo   Mycophenolic acid is a potent inhibitor of angiogenesis Arteriosclerosis, thrombosis, and vascular biology, 2006; 26(10): 2414-6.
Kamata Masakazu, Wu Raymond P, An Dong Sung, Saxe Jonathan P, Damoiseaux Robert, Phelps Michael E, Huang Jing, Chen Irvin S Y   Cell-based chemical genetic screen identifies damnacanthal as an inhibitor of HIV-1 Vpr induced cell death Biochemical and biophysical research communications, 2006; 348(3): 1101-6.
Winssinger Nicolas, Damoiseaux Robert, Tully David C, Geierstanger Bernhard H, Burdick Keith, Harris Jennifer L   PNA-encoded protease substrate microarrays Chemistry & biology, 2004; 11(10): 1351-60.
Warmuth Markus, Damoiseaux Robert, Liu Yi, Fabbro Doriano, Gray Nathanael   SRC family kinases: potential targets for the treatment of human cancer and leukemia Current pharmaceutical design, 2003; 9(25): 2043-59.
Damoiseaux Robert, Schultz Peter G, Johnsson Kai   Towards the generation of artificial O6-alkylguanine-DNA alkyltransferases: in vitro selection of antibodies with reactive cysteine residues Chembiochem : a European journal of chemical biology, 2002; 3(6): 573-5.