FACULTY RESEARCH

Faculty List

Gautam Chaudhuri, M.D., M.B.B.S., Ph.D.

Work Email Address: gchaudhuri@mednet.ucla.edu

Work Phone Number: 310-206-2057
310-206-6575

Health System

Office Address:
22-184 CHS
CAMPUS - 174017
CA

Work Address:
10833 Le Conte Avenue
LOS ANGELES, CA 90095

Department / Division Affiliations
Chair, and Professor, Obstetrics and Gynecology
Professor, Molecular & Medical Pharmacology
Member, Internal Advisory Board, CTSI, JCCC Signal Transduction and Therapeutics Program Area, Workforce Development

Research Interests
Studies are carried out on the mechanism by which estradiol and nitric oxide modulate various physiological functions and the signal transduction pathways involved. The major focus is on the cardiovascular system and breast cancer.


Publications

A selected list of publications:

van Nas, Guhathakurta, Wang, Yehya, Horvath, Zhang, Ingram-Drake, Chaudhuri, Schadt, Drake, Arnold, Lusis   Elucidating the Role of Gonadal Hormones in Sexually Dimorphic Gene Co-Expression Networks Endocrinology, 2008; .
Pervin Shehla, Singh Rajan, Chaudhuri Gautam   Nitric oxide, N omega-hydroxy-L-arginine and breast cancer Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society, 2008; 19(2): 103-6.
Souter, Huang, Martinez-Maza, Crabb Breen, Decherney, Chaudhuri, Nathan   Serum levels of soluble vascular cell adhesion molecule-1, tumor necrosis factor-alpha, and interleukin-6 in in vitro fertilization cycles Fertility and sterility, 2008; .
Pervin Shehla, Tran An H, Zekavati Shaghayegh, Fukuto Jon M, Singh Rajan, Chaudhuri Gautam   Increased susceptibility of breast cancer cells to stress mediated inhibition of protein synthesis Cancer research, 2008; 68(12): 4862-74.
Chaudhuri Gautam   Nuclear receptors and female reproduction: a tale of 3 scientists, Jensen, Gustafsson, and O'Malley Reproductive sciences (Thousand Oaks, Calif.), 2008; 15(2): 110-20.
Friedlander Arthur H, Chaudhuri Gautam, Altman Lisa   A past medical history of gestational diabetes: its medical significance and its dental implications Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2007; 103(2): 157-63.
Hayashi Toshio, Esaki Teiji, Sumi Daigo, Mukherjee Tapan, Iguchi Akihisa, Chaudhuri Gautam   Modulating role of estradiol on arginase II expression in hyperlipidemic rabbits as an atheroprotective mechanism Proceedings of the National Academy of Sciences of the United States of America, 2006; 103(27): 10485-90.
Souter Irene, Janzen Carla, Martinez-Maza Otoniel, Breen Elizabeth Crabb, Stanczyk Frank, Chaudhuri Gautam, Nathan Lauren   Serum levels of soluble vascular cell adhesion molecule-1 are decreased in women receiving oral contraceptives compared with normally menstruating women: implications in atherosclerosis Fertility and sterility, 2005; 83(5): 1480-8.
López-Jaramillo Patricio, Díaz Luis Alfonso, Pardo Alberto, Parra Gustavo, Jaimes Hermes, Chaudhuri Gautam   Estrogen therapy increases plasma concentrations of nitric oxide metabolites in postmenopausal women but increases flow-mediated vasodilation only in younger women Fertility and sterility, 2004; 82(6): 1550-5.
Han Tae H, Qamirani Erion, Nelson Allyson G, Hyduke Daniel R, Chaudhuri Gautam, Kuo Lih, Liao James C   Regulation of nitric oxide consumption by hypoxic red blood cells Proceedings of the National Academy of Sciences of the United States of America, 2003; 100(21): 12504-9.
Mukherjee Tapan K, Nathan Lauren, Dinh Hillary, Reddy Srinivasa T, Chaudhuri Gautam   17-epiestriol, an estrogen metabolite, is more potent than estradiol in inhibiting vascular cell adhesion molecule 1 (VCAM-1) mRNA expression The Journal of biological chemistry, 2003; 278(14): 11746-52.
Berman Jennifer R, Almeida Fernando G, Jolin Julie, Raz Shlomo, Chaudhuri Gautam, Gonzalez-Cadavid Nestor F   Correlation of androgen receptors, aromatase, and 5-alpha reductase in the human vagina with menopausal status Fertility and sterility, 2003; 79(4): 925-31.
Mukherjee Tapan K, Dinh Hillary, Chaudhuri Gautam, Nathan Lauren   Testosterone attenuates expression of vascular cell adhesion molecule-1 by conversion to estradiol by aromatase in endothelial cells: implications in atherosclerosis Proceedings of the National Academy of Sciences of the United States of America, 2002; 99(6): 4055-60.
Campisi Roxana, Nathan Lauren, Pampaloni Miguel Hernandez, Schöder Heiko, Sayre James W, Chaudhuri Gautam, Schelbert Heinrich R   Noninvasive assessment of coronary microcirculatory function in postmenopausal women and effects of short-term and long-term estrogen administration Circulation, 2002; 105(4): 425-30.
Nathan L, Pervin S, Singh R, Rosenfeld M, Chaudhuri G   Estradiol inhibits leukocyte adhesion and transendothelial migration in rabbits in vivo : possible mechanisms for gender differences in atherosclerosis Circulation research. , 1999; 85(4): 377-85.
Pervin Shehla, Chaudhuri Gautam, Singh Rajan   NO to breast: when, why and why not? Current pharmaceutical design, 2010; 16(4): 451-62.
Pervin Shehla, Singh Rajan, Chaudhuri Gautam   Nitric-oxide-induced Bax integration into the mitochondrial membrane commits MDA-MB-468 cells to apoptosis: essential role of Akt Cancer research, 2003; 63(17): 5470-9.
Fung Camille, Evans Edward, Shin Don, Shin Bo-Chul, Zhao Yuanzi, Sankar Raman, Chaudhuri Gautam, Devaskar Sherin U   Hypoxic-ischemic brain injury exacerbates neuronal apoptosis and precipitates spontaneous seizures in glucose transporter isoform 3 heterozygous null mice Journal of neuroscience research, 2010; 88(15): 3386-98.
Janzen Carla, Sen Suvajit, Cuevas Janis, Reddy Srinivasa T, Chaudhuri Gautam   Protein phosphatase 2A promotes endothelial survival via stabilization of translational inhibitor 4E-BP1 following exposure to tumor necrosis factor-α Arteriosclerosis, thrombosis, and vascular biology, 2011; 31(11): 2586-94.
Sen Suvajit, Kawahara Brian, Chaudhuri Gautam   Mitochondrial-associated nitric oxide synthase activity inhibits cytochrome c oxidase: implications for breast Cancer Free radical biology & medicine, 2013; 57: 210-20.
Pervin Shehla, Hewison Martin, Braga Melissa, Tran Lac, Chun Rene, Karam Amer, Chaudhuri Gautam, Norris Keith, Singh Rajan   Down-regulation of vitamin D receptor in mammospheres: implications for vitamin D resistance in breast cancer and potential for combination therapy PloS one, 2013; 8(1): e53287.