FACULTY RESEARCH

Faculty List

Yushen Du

Email Address: yushendu@mednet.ucla.edu

Work Phone Number: 310-794-5557

Mailing Address:
10-638 Factor Building
690 Charles E. Young Drive
Los Angeles, CA 90095

Department / Division Affiliations
Assistant Professor, Molecular & Medical Pharmacology

Research Interests
  • Quantitative High-throughput Genomics

  • Developed a quantitative and high-throughput genetics system for RNA viruses, including influenza virus, HIV, HCV and Zika virus.
  • Established a systematic method to identify and annotate functional residues of a given viral protein.
  • Established an influenza HIS vaccine strain by combining IFN sensitive mutations across the entire viral genome. 
  • Examined the safety and efficacy of HIS vaccine in mouse and ferret models.
  •  

    Protein Interactome

  • Established exon/cDNA library-based mRNA display-deep sequencing platform for studying protein-protein interactome or drug-protein interactions, with high sensitivity and accuracy.
  • Examined influenza viral-host interactome by coupling mRNA display platform with Mass Spectrometry.
  • Determined the cellular interacting partner of a Chinese medicine derived small chemical: martynoside; and studied the mechanism of it facilitating hematopoiesis.


Publications

View a up-to-date publication list: Publications